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endocrine system
| Question | Answer |
|---|---|
| define gland | an organ that secretes a substance |
| describe exocrine glands | secrete substances via ducts to the outside of the body |
| describe endocrine glands | secrete hormones directly into blood capillaries |
| describe true endocrine glands | produce only hormones |
| describe endocrine tissue | tissues found in organs that produce hormones, yet function in other ways as well |
| name the 6 true endocrine glands | hypophysis, thyroid, adrenals, thymus, pineal, parathyroid (hey take away those pitiful puppies) |
| name the 10 places endocrine tissue can be found | heart, lungs, testes, ovaries, stomach, small intestine, pancreas, hypothalamus, kidneys, placenta (if pregnant) |
| which endocrine glands originate from the ectoderm? | pineal, hypophysis, adrenal medulla |
| which endocrine gland originates from the mesoderm? | adrenal cortex |
| which endocrine glands originate from the endoderm? | thymus, thyroid, parathyroid |
| name and describe the two local types of hormones | autocrines: act on themselves paracrines: act on nearby cells |
| define amine | hormone comprised of one type of amino acid |
| name the amines | histamines, triptophan, tyrosine, T3 & T4 |
| all amines are _____ soluble, except for __ & __, which are _____ soluble. | water, T3 & T4, lipid |
| where are amines manufactured? | RER of the secreting cell |
| target cell receptors are specific ________ | proteins |
| define up-regulation | target cell receptors increase in number to maintain homeostasis |
| define down-regulation | target cell receptors decrease in number to maintain homeostasis |
| which is more common: down-regulation or up-regulation? | down-regulation |
| a hormone's presence on a receptor activates the _ protein | G |
| what does the activation of the G protein stimulate? | an enzyme called adenylate cyclase, which splits ATP |
| as adenylate cyclase splits ___, a free _ is given off to form ___. ___ releases a free protein to become ____ | ATP, P, ADP, ADP, cAMP |
| what does cAMP's presence stimulate? | protein kinases which pick up all free Ps, causing protein alteration |
| define phosphorylation of protein | the process of adding free Ps to existing proteins |
| what is the most common form of protein alteration? | phosphorylation |
| how do lipid soluble hormones interact with target cells? | slip through the cell membrane and enter the target cell |
| the lipid soluble hormone attaches to the intracellular receptor, forming a _______-________ ________ | hormone-receptor complex |
| where does the hormone-receptor complex bind? | receptor proteins on the chromatin of DNA |
| during transcription, the hormone-receptor complex alters the strand of ____ | mRNA |
| during translation, ____ assembles a new protein from the altered ____ strand | tRNA, mRNA |
| name the three ways hormones interact with other hormones | permissively, synergistically, antagonistically |
| what happens when hormones interact permissively? | involves two hormones, one paves the way for the action of another (FSH paves the way for estrogen) |
| what happens when hormones interact antagonistically? | the action of one hormone opposes another (glucagon and insulin, CT and PTH) |
| what happens when hormones interact synergistically? | more than two hormones interact to achieve a common goal most common form of interaction |
| what does a feedback system do? | aids in the control of hormone secretion |
| name the three components of a feedback system | receptor, brain, effector |
| which is more common: positive or negative feedback? | negative |
| define negative feedback | output counteracts the input |
| define positive feedback | output intensifies the input |
| negative feedback has a ___________-__________ effect | stimulatory-inhibitory |
| positive feedback has a ___________-___________ effect | stimulatory-stimulatory |
| in what three cases does positive feedback occur? | labor, clotting, disease |
| name the three modes of negative feedback that control hormonal secretion | hormonal, humoral, neural |
| describe the hormonal mode of negative feedback | hormones control the secretion of other hormones |
| describe the humoral mode of negative feedback | blood levels of hormones control the secretion of other hormones |
| describe the neural mode of negative feedback | nerve impulses control the secretion of hormones |