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Vet Osteopathology
Veterinary Pathology of the Skeletel System 227.301 1st Sem
| Question | Answer |
|---|---|
| 3 cellular elements of bone tissue are ________, ________ & ________. | osteoblasts, osteocytes, osteoclasts |
| Osteoblasts manufacture ________ and ________. | osteoid, regulatory factors |
| Osteoid is the ________ component of ________. | organic, bone matrix |
| Osteoblasts mediate bone ________ by ________. | resorption, osteoclasts |
| Osteoblasts initiate ________ of osteoid. | mineralization |
| Regulatory factors produced by osteoblasts are important in ________. | bone remodeling |
| Osteoclasts originate from ________. | monocytes |
| Osteoblasts and osteocytes are derived from ________. | osteoprogenitor cells |
| Osteoblasts at a site of active bone formation are ________, while those not producing bone are ________. | plump, flat |
| Osteoblasts are called ________ once they become surrounded by ________ and embedded in ________. | osteocytes, osteoid, bone |
| The cellular morphology of an osteoblast includes an ________ nuclei, a ________ cytoplasm, and a prominent ________. | eccentric, basophilic, Golgi zone |
| Plasma cells, like _______, have _______ nuclei, _______ cytoplasms, and prominent _______, but can be distinguished from _______ because they are much _______. | osteoblasts, eccentric, basophilic, Golgi zones, osteoblasts, smaller |
| To function normally, osteoblasts need the _______ ability to synthesize _______ and appropriate _______ for _______ production. | genetic, osteoid, substrates, osteoid |
| The disease _______ is characterized by a _______ defect in _______. This defect interferes with the cell's ability to synthesize _______. | osteogenesis imperfecta, genetic, osteoblasts, osteoid |
| Osteoblasts that undergo _______ transformation cause _______. | malignant, osteosarcoma |
| Osteosarcoma is a _______ common and _______ malignant tumour in _______. It is _______ common in _______ and _______ in other _______. | very, highly, large-breed dogs, less, cats, rare, domestic animals |
| _______ are the most abundant cells of bone tissue. | Osteocytes |
| Osteocytes reside in _______ and are surrounded by _______. | lacunae, mineralized matrix |
| Osteocytes maintain contact with other osteocystes and the bone surface via _______. | canaliculi |
| Nutrients are supplied to osteocytes, and waste is eliminated, through _______. | canaliculi |
| Osteoclasts are involved in _______ homeostasis through _______ action on _______ bone _______. | calcium, local, perilacunar, matrix |
| Osteocytes are replaced throughout life by _______. | remodeling processes |
| Osteclasts are primarily responsible for _______. | bone resporption |
| Shallow pits on bone surfaces are called _______. | Howship's lacunae |
| Osteoclasts are _______, _______ cells with _______ cytoplasm. | large, multinucleated, eosinophilic |
| Osteoclasts have a _______ border that is contiguous with the _______ when it is undergoing _______. | ruffled, bone surface, resorption |
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