click below
click below
Normal Size Small Size show me how
Turnicky 06 Hemostas
Turnicky: Hemostasis
Question | Answer |
---|---|
Formation of a platelet plug | Primary hemostasis |
Formation of fibrin through the coagulation cascade | Secondary hemostasis |
Formation of plasmin for breakdown of the clot | Tertiary hemostasis |
Vitamin K dependent factors | II VII IX X |
Needed for post-ribosomal attachment of COOH to glutamic acid | Vitamin K |
COOH provides... | Ca receptor essential for binding the factor to phospholipid |
Monitor in coumadin therapy | PT time |
Monitor in heparin therapy | aPTT time |
Intrinsic Pathway time | aPTT |
Extrinsic pathway time | PT |
Common pathway time | Thrombin time |
Contains mediators of platelet function, ADP, ATP, Ca, and serotonin | Platelet dense bodies |
Contains hemostatic proteins: fib, FV, vWF, PAI-I and plasminogen | Platelet alpha granules |
Most numerous platelet granules | Alpha granulues |
Platelet adhesion | Attachment of platelets to something besides other platelets |
Platelet aggregation | Attachment of platelets to one another |
Platelet secretion | Discharge of granular contents into the surrounding area |