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Integumentary System
Epidermis
| Question | Answer |
|---|---|
| Cells of epidermis -L- | -keratinized stratified squamous epithelium -keratinocytes, melanocytes, Merkel cells, and Langerhans' cells |
| keratinocytes -K- | epidermal cell that produces keratin, gives the epidermis its protective properties (waterproofing) |
| melanocytes -L- | epithelial cells of epidermis that synthesize and secrete melanin, found in the deepest layer of epidermis |
| melanosomes | membrane-bound granules where melanin is accumulates, protects keratinocyte nucleus from UV |
| Langerhans' cells -L- | AKA dendritic cells, phagocytes that ingest foreign substances and help activate our immune system, migrate from bone marrow to epidermis |
| Merkel Cells -L- | present at epidermal-dermal junction, associated with a dermal nerve endings. -acts as a sensory receptor for touch |
| Merkel disc | functions as a sensory receptor for touch |
| Layers of Epidermis (Deept to Superficial) | stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum |
| stratum basale structure -L- | deepest layer of epidermis, has single row of cells, young keratinocytes,small number of melanocytes and merkel cells, occasionall merkel cells are present |
| stratum spinosum -L- | 8-10 rows of keratinocytes that appear irregular in shape. langerhans' and melanosomes conneced by desmosomes |
| stratum granulosum -L- | 3 to 5 layers flat keratinocytes with disintegrating organelles - keratohyalin granules and lamellated granules occure |
| keratohyaline granules | found in stratum granulosum, helps to from keratin in the upper layers of epidermis |
| lamellated granules | found in stratum granulosum, contains waterproofing glycolipid that is a major factor in slowing water loss across the epidermis |
| stratum lucidum -L- | 2-3 rows of clear, flat, dead keratinocytes. Present in only thick skin |
| stratum corneum -L- | outer most layer of epidermis, consist of 20 -30 dead keratinocytes filled with keratin and connected by glycolipids. - thickes layer of epidermis |
| stratum basale function -L- | mitosis to replace cells lost superficially. - melanin production. - touch |
| stratum spinosum function -L- | keratin production begins. - some mitosis begins |
| stratum corneum -L- | waterproofing |
Created by:
karin.thompson
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