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Chpt - 1
Intro to Pharm & History of Drugs
| Question | Answer |
|---|---|
| some __ __ replacement therapy drugs are derived from yams | estrogen hormone |
| willow bark is a plant source of | aspirin |
| involves descriptions of how drugs move through the body to be absorbed, distributed, metabolized and excreted | pharmacokinetics |
| source of the pain medication, morphine | opium |
| patients taking certain diuretics are prone to develop a loss of __, vital to cardiac and other body cells proper functioning | potassium |
| pregnant women should not take the drug | thalidomide |
| examples of __ __ are of vitamins, minerals, and herbs | dietary supplements |
| OTC drug has a __ rate of side effects and toxicity | low |
| atropine and scopolamine are derived from | belladonna plant |
| disease was controlled first through pharmaceutical research and development | epilepsy |
| derived from an old remedy using the foxglove plant and is still used today to treat congestive heart failure | Digoxin (Lanoxin) |
| derived from a Chinese remedy for respiratory ailments, __ is found in certain over the counter bronchodilator drugs | ephedrine |
| terms medication and drug can be used interchangeably, but the term, __, can also be used to name illicit chemical substances | drug |
| passage of this, to the FDA act, addressed tougher controls on prescriptions and on new drugs in response to the thalidomide tragedy | 1962 Kefauver-Harris amendment |
| indication that a pharmacy dispensed bottle of pills contains controlled substance would be | large C enclosing a Roman numeral |
| Digoxin and __ are derived from the foxglove plant to treat congestive heart failure | digitalis |
| abbreviation for the federal act of 1996 that requires all drug information be kept secure and information is released only to authorized persons | HIPAA |
| symbol __, derived from Latin word recipe meaning take, indicates a prescription that combines ingredients that form a drug | Rx |
| Mrs. Peace used a tea made of rose hips to provide her with a tasty source of | vitamin C |
| minims, drams, and scruples refer to the __ system of measurement of drugs | Apothecary |
| controlled substances are also known as | schedule drugs |
| federal agency abbreviated __ reviews data that pharmaceutical firms offer proving the safety of a medication that they want to eventually market | FDA |
| the __ is the federal agency that oversees the marketing and dispensing of schedule drugs | DEA |
| 1983 the legislation __ was passed to give incentives to pharmaceutical firms to research and market drugs for rare illnesses | Orphan Drug Act |
| 1912 the federal government used the US Pharmacopeia or __ to give a listing of drugs that could be prescribed | National Formulary |
| therapeutic use for reserpine | hypertension |
| therapeutic use for dilantin | epilepsy |
| therapeutic use for insulin | diabetes mellitus |
| therapeutic use for colchicine | gout |
| therapeutic use for haldol | psychosis |
| therapeutic use for Tagamet | heartburn/peptic ulcer |
| therapeutic use for Dramamine | motion sickness & vomiting |
| therapeutic use for quinine | malaria |
| therapeutic use for Zivovudine | AIDS |
| response to certain drugs differ between people because of | pharmacogenetics |
| schedule drugs are drugs with | potential for abuse |
| amendment defined prescription drugs | Durham-Humphrey |
| how drugs produce their effects based on time & dose is | pharmacodynamics |
| drugs are used to affect the body therapeutically through | pharmacotherapy |
| using genome technology to discover new drugs is | pharmacogenmics |
| contraceptive drugs belong to the category of | prophylaxis |
| study of the chemical structures of drugs and the action of drugs at the molecular level within cells | molecular pharmacology |
| mechanism of action by which drugs produce their effects (desired or undesired) based on time and dosage | pharmacodynamics |
| drug deliberately administered for its medicinal value as preventive, diagnostic, or therapeutic agent | medicine |
| drug can refer to chemical substances that __ __ have preventative, diagnostic, or therapeutic use | do not |
| defined as the study of drugs and their interactions with living organisms | pharmacology |
| control or improve symptoms, like an antibiotic to kill the bacteria that causes an infection, or hormone replacement drugs for menopause | therapeutic use |
| keep a symptom from happening, like a vaccination against a viral disease, or using a Transderm Scop patch to prevent sea sickness | preventative use |
| often used with x-rays as contrast media; can be given to simulate symptoms for some scan or test, like increased heart rate for stress test | diagnostic use |
| Ancient drugs were prepared according to __ __ involving drying, crushing, & combining variety of plants, substances from animals & minerals | standard recipes |
| 1600s, patients advised to __ __ to cure blood in the urine | eat soap |
| 1600s, patients advised to put __ in beer to cure intestinal worms | mercury |
| contained the names of 800 different herbal formulations and prescriptions | Ebers Papyrus |
| Egyptians extracted the oil from plants known for __ __ | healing properties |
| King Tutankhamum’s tomb had 350 __ jars of plant oils in it | alabaster |
| emphasized use of herbs and some minerals; herbal preparations were used in conjunction with acupuncture, massage, & exercise; used few animals products | Chinese |
| wrote first Chinese book on herbal medicine; contained 365 different herbal remedies | Shen Nong |
| means recipe, or “take this” | Rx |
| Rx indicates a __, which is a combining of ingredients into a drug | prescription |
| Belladonna means __ __ in Italian | beautiful lady |
| Women used to use belladonna to | dilate their pupils |
| comes from pregnant mares’ urine | Premarin |
| Colchicine is derived from __ __ known as Colchicum autumnale | autumn crocus |
| Aztec Indians of Mexico | grew herbs with medicinal properties |
| maintained royal gardens of medicinal plants | Montezuma |
| furthered the study of medicine with important first steps | Greeks & Romans |
| Alzheimer’s drug galantamine (Razadyne) is derived from | daffodil bulbs |
| drugs dissolved into plant sources | gums, oils, bases |
| composed of dried (desiccated) animal thyroid gland tissue | thyroid supplement drugs |
| common ingredient of topical skin drugs; obtained from the purified fat of sheep's wool | lanolin |
| in the past, only source from ground-up animal pancreas | insulin |
| contains red iron oxide as an inert ingredient | quinapril (Accupril) |