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Antiviral OSU

OSU-CHS virology

QuestionAnswer
blocks protein processing + assembly, PI for HIV Atazanavir Fosamprenavir Lopinavir Ritonavir
Foscarnet, PFA or PAA Binds and inhibits herpesvirus DNA polymerase HSV, CMV
Immunoglobulin Blocks attachment or penetration HAV, HBV, CMV, Rabies, RSV, Measles, VZV
Enfuvirtide (Fuzeon) Blocks attachment or penetration, gp41 analog for HIV
Zinc gluconate, Zinc acetate Blocks attachment or penetrartion, Binds to zinc finger domains in VAP for Cold viruses
Amantadine, Rimantadine Blocks M2 ion channels, Inhibits dissassembly and penetration of Influenza A
Interferon alpha Blocks transcription, protein synthesis HAV, HBV, HCV, HPV…
Pleconaril Blocks uncoating, Binds to picornavirus capsid picornaviruses
Oseltamivir (Tamiflu), Zanamivir (Relenza) Inhibits neuraminidase, Virus egress for Influenza A + B
Entecavir (Baraclude) Nucleoside analog, Lamivudine (3TC, Epivir) Inhibits reverse transcriptase for HBV
Efavirenz Non-nucleoside analog, Inhibits reverse transcriptase HIV
Telbivudine (Tyzeka) Nucleoside analog, Causes DNA chain termination chronic HepB
Ganciclovir Nucleoside analog, Causes DNA chain termination for CMV
Acyclovir Nucleoside analog, Causes DNA chain termination for HSV, VZV
Zidovudine (AZT) Nucleoside analog, Causes DNA chain termination for HIV
Ribovarin Nucleoside biosynthesis, mRNA capping for RSV, HBV + other RNA viruses
Adefovir Reverse transcriptase inhibitor for HBV
Tenofovir NucleoTide analog, Causes DNA chain termination for HIV
Created by: vpack87