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ANS NMC

ANS- PNS, SNS differences & functions

QuestionAnswer
Sympathetic system has a broader distribution, innervating effectors throughout the body SNS fibers= ramification. SNS pregang fibers may traverse many ganglia bf terminiating post-gangl cell. Synaptic arborization = single preganglionic fiber terminating on many post-ganglionic cells. = the basis for the diffuse nature of SNS response.
Parasympathetic system is relatively limited The PNS has its terminal ganglia near the end-organ. Sometimes 1:1 ratio relationship between pre-end post-ganglionic fibers. The ratio between preganglionic vagal fibers and ganglion cells may be much higher, e.g. 1:8000 for Auerbach's plexus.
SNS anatomy Cell bodies of preganglionic fibers: found in intermediolateral columns of the spinal cord (first thoracic to second or third lumbar segments
SNS anatomy Preganglionic fiber axons synapse with sympathetic ganglionic neurons which lie outside the cerebrospinal axis. Sympathetic ganglia are found at three sites: Paravertebral, Prevertebral, Terminal
SNS Paraverebral ganglia- 22 interconnected pairs on either sides of the vertebral column. (para: Gr: at the side of along side)- Myelinated preganglionic fibers (white rami: thoracolumbar outflow only) leave through the anterior spinal roots.
SNS Paraverebral ganglia- Postganglionic fibers (gray rami) runs back to spinal nerves for distribution to: blood vessesls of the skin , blood vessels of skeletal muscle, sweat glands, pilomotor muscles
Prevertebral Ganglia: abdominal and pelvic location, comprised of: - celiac ganglia -superior mesenteric ganglia - aorticorenal and inferior mesenteric ganglia
SNS Post ganglia fibers- All postganglionic fibers arise from cell bodies located within these ganglia; the preganglionic fibers come from upper thoracic segments: No sympathetic preganglionic fibers come from above the first thoracic level
Terminal Ganglia: few, residing near the innervated organ, including 1) ganglia associated with the urinary bladder and rectum 2) cervical ganglia (neck): three ganglia (chain) mediating vasomotor, secretory, pupillodilatory and pilomotor responses of the head and neck)
Adrenal medulla (top of kidney) is similar to sympathetic ganglia. Difference: a) Epinephrine is released (post-ganglionic sympathetic fibers release norepinephrine) b) Chromaffin cells are innerved by preganglionic fibers that release acetylcholine.
PNS Cranial-Sacral outflow 1) Midbrain Long Pregang fibers target Cilary ganglion of the orbit
PNS Cranial-Sacral outflow 2) Medulla Oblongata Long preganglionic fibers- CNs - 7, 9, 10 7- submax, sublingual and sphenopalatine 9- otic 10- many thoracic and visceral ganglia
PNS Cranial-Sacral outflow 3) Sacral Long pregang fibers- terminate in or near bladder, rectum and sex organs
PNS Long Pre-ganglionic Fibers, Short Post "Para= Long Pre" Pre to Post= Ach/Nicotinic Post to Site=Ach/nicotinic/muscarinic
SNS Short Pre- long Post "Have sympathy that the Post-age took so Long" Pre to Post=ach/nicotinic Post to Site=Norepin/ a, b1, b2 receptors
Adrenal Nerve to Adrenal gland= Ach/nicotinic on adrenal gland= epinepherine (80%), Norepin (20%)
Somatic Nerve to terminal skeletal muscle= ach/nicotinic
Created by: nmctelos