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m6 Lymphatic

Lymphatic Capillaries Extend into interstitial spaces forming complex networks that parallel those of blood capillaries.
Lymphatic Ducts Two vessels that drain fluid into the venous system and are formed from the merging of the lymphatic trunks.
Hydrostatic pressure movies fluid into lymph capillaries
How does lymph move? breathing and dkeletal muscle and smooth muscle in the lymphatic trunk walls contract moving fluid forward. Valves in vessells prevent back flow.
Thymus A bi-lobed organ composed of lymphatic tissue encased in connective tissue. Releases thymosin with stimulates maturation of T calls. This is where T-Cells "grow up"
Spleen Filters blood instead of lymph. White pulp contains lymphocytes. Red: Surround venous vessels. Blood is filtered in this space.
1st line of defense Hair, skin, mucous membranes, respiratory tract lining, digestive, urinary, and reproductive systems.
2nd line of defense Chemical barriers. Gastric juice. Tears. Salts from perspiration. Interferons. Fever. Inflammation. Heat. Pus. Pain. Phagocytosis.
Interferons Enhance ability of other defense mechanisms. Stimulate protein synthesis that is responsible for blocking replication of viruses.
Phagocytosis Removes foreign particles from the lymph and blood. Leukocytes and macrophages.
3rd Line of defense immunity and resistance.
T-Cell Secretes cytokines that enhance cellular response to antigens. Secretes frowth inhibiting factors that prevent cell growth. Secretes interferon that inhibits the proliferation of viruses and tumor cells.
Suppressor T-Cell Stops attack. Differentiate into killer t-cells with subsequent exposure.
Helper T-Cells Activate b-cells to produce antibodies
B-Cell formed in red bone marrow. Respond to antigens through use of antibodies.
Primary immune response(first attack by pathogen) B-cells and t-cells activated after encountering antigen. Antibodies released. 5-10 days for blood detectable levels. Production continues for several weeks. Some b-cells remain dormant as memory cells.
Secondary immune response(another attack by previous pathogen) Antigen encountered by memory cell. B-cell enlarges and prodcues many anti-bodies. 1-2 days for detectable levels.
Active immunity(artificial) (immunity gained through a vaccine)
Passive immunity(natural) (immunity given through umbilical cord)
Passive immunity(artificial) (immunity given through an anti-serum)
Isoimmunity (pregnancy, organ transplant)mediated by immunosuppressive drugs.
Autoimmunity Body attacks itself
Created by: paulgrant



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