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Human Parasitology1

Exam 1

What drugs does a rapid impact package contain and what diseases are targeted? Ivermectin for onchocerciasis &lymphatic filariasis, Albendazole for Soil-Transmitted Helminths, Azithromicin for Trachoma, Praziquantel for Schistosomiasis
What are the six kingdoms in the tree of life? Eubacteria, Archaebacteria, Protista, Plantae, Animalia, & Fungi
In which kingdoms do we find the traditional parasites? Protista & Animalia
In which kingdom and phylum are the trematodes classified? Kingdom Animalia, Phylum Platyhelminthes
Which parasites are commonly found in the small intestine of the human DH? Fasciolopsis buski, Metagonimus yokagawai, Heterophyes heterophyes
Which parasites are commonly found in the liver/bile duct of the human DH? Fasciola hepatica, Clonorchis sinensis
Which parasites are commonly found in the lung tissue of the human DH? Paragonimus westermani
Which parasites are commonly found in the bloodstream of the human DH? Schistosomes (S. mansoni, S. japonicum, S. haematobium)
Describe the procedure for Formalin Ethyl-Acetate Sedimentation. 4g of feces -> add formalin -> strain through gauze to get big things out -> centrifuge -> decant + discard supernatant -> more formalin -> ethyl acetate -> centrifuge -> discard supernatant. Eggs are in sediment.
What are definitive morphological features of Metagonimus yokagawai and Heterophyes heterophyes. 1.4 mm * 0.5 mm Metagonimus yokagawai- ventral sucker and gonotyl fused lateral to the midline of the body (genito- acetabulum). Heterophyes heterophyes has separate ventral sucker and gonotyl structures along midline
What pathology is caused by the Fasciola hepatica juveniles in the definitive host? Juveniles: pain, irritation, hoarseness, coughing upon ingestion. acute fascioliasis. headache, backache, chills, fever. ulceration + calcification in ectopic sites. mechanical damage to liver -> Hepatomegaly -> ruptured Glisson's capsule. worst @ 8 wks.
What pathology is caused by the Fasciola hepatica adults in the definitive host? Adults: chronic fascioliasis. diarrhea. anemia. common bile duct blockage. proline secretion -> collagen and fibrous tissue buildup in bile duct walls-> pipestem fibrosis. Fibrotic bile duct -> backflow of bile -> cirrhosis, jaundice, hepatomegaly.
Created by: sonnybobiche