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Anatomy Unit 2

TermDefinition
skin (cutaneous membrane) largest organ of the body
epidermis and dermis two main parts of the skin
epithelial tissue tissue of epidermis
connective tissue tissue of the dermis
subcutaneous layer lies beneath the skin and is NOT part of the skin
hair, glands, nails accessory structures of integumentary system
protection, prevent h2o loss/gain, metabolic regulation, absorption/secretion, immune functions epidermis functions
temp regulation, secretion/absorption, sensory reception dermis functions
epidermis thin, superficial layer of skin, avascular, keratinized stratified squamous
keratinocytes 90% of epidermis, produce keratin, lamellar granules contribute to water repellency
melanocytes 8% of epidermis, produce melanin, projections between keratinocytes, melanin absorbs UV light/protect keratinocytes
intraeptdermal macrophages (Langhans cells) Originate from red bone marrow and migrate to epidermis, immune response, destroy microbes
tactile epithelial cells (Merkel cells) located in stratum basale, touch sensation, tactile disc
basale, spinosum, granulosum, lucidum, corneum order of epidermal strata
stratum basale deepest layer, active mitosis, tonofilaments, desmosomes and hemidesmosomes, melanocytes, Merkel cells
stratum spinosum 8-10 layers; spiny, strong and flexible, keratin intermediate fibers, desmosomes, absorbs melanin, superficial cells flatten
stratum granulosum transitional zone, about 3-5 layers, flat, dying cells, apoptosis, lamellar granules, water-repellant; keratohyalin contributes to keratin
stratum lucidum only in thick skin like fingertips, palms, and soles; 4-6 layers of clear flat, dead keratinocytes filled with keratin
stratum corneum outermost; about 25-30 layers in thin skin and 50+ in thick skin; dead keratinized water repellant cells; constantly shed
epidermal growth newly formed cells in stratum basale pushed upward cells undergo keratinization/apoptosis as they move towards surface 4-6 weeks from basale to corneum EGF simulates growth of ep. cells/fibroblasts
EGF Epidermal Growth Factor
Dermis thickest layer and deep to the epidermis; made of dense irregular connective tissue w/ collagen and elastic fibers
accessory structures of dermis glands, hair, nerves, blood vessels
papillary and reticular layer regions of the dermis
papillary layer superficial/thin; 20% of dermis; areolar CT
dermal papillae; capillary loops; meissner''s corpuscles; free nerve endings how to recognize papillary layer
reticular layer deep/thicker; dense irregular connective tissue; net-like arrangement
hair follicles, nerves, sebaceous glands, sudoriferous glands how to recognize reticular layer
Meissner's corpuscles associated with touch sensations
free nerve endings associated with warmth, cool, pain, and itch
root plexus sensitive to touch around hair follicles
tension lines reflect direction of underlying collagen fibers
perpendicular what incision creates more scarring?
parallel what incision creates thinner, finer scars
found over most of the body except palms, soles, and a few small areas where is hair found?
epidermis where do hair and follicles develop from
hair columns of dead, keratinized epidermal cells
shaft visible part of hair
root embedded in dermis
hair follicle surrounds root
bulb swollen portion surrounding root
hair matrix innermost layer of follicle; site of growth
papilla cluster of capillaries beneath the hair matrix
root plexus sensitive to touch
arrestor pili associated with goose bumps
5 in how much does hair grow per year
growth stage matrix divides and pushes hair; 2-6 years
regression stage matrix stops dividing; 2-3 weeks
resting stage last stage; new growth cycle begins; 3 months
sebaceous gland function lubricates hair/skin; secretion increases during adolescence
sebaceous gland location/product connected to hair follicles; secrete sebum
sebaceous gland classification/mechanism holocrine; simple branched acinar
ceruminous gland function contributes to earwax; provides sticky barrier against foreign bodies
ceruminous gland location/product external ear canal; modified sweat gland; secretes cerumen
ceruminous gland classification/mechanism apocrine
eccrine sweat gland function produces sweat/is involved in maintaining body-temp homeostasis
eccrine sweat gland location/product most numerous in forehead, palms, soles, excretory portion in deep dermis
eccrine sweat gland classification/mechanism merocrine; simple coiled tubular
apocrine sweat gland function more viscous secretion w/ lipids/proteins; interacts w/ bacteria for body odor
apocrine sweat gland location/product axilla, groin, areolae of breasts, bearded regions of males, duct opens into hair follicles
apocrine sweat gland classification/mechanism merocrine mechanism; simple coiled tubular
nails consist of epidermal cells converted to hard keratin
nail body visible part of each nail
root part in groove hidden by cuticle
lunula moon-shaped white area near root
nail bed layer of epithelium under nail body; contains abundant BV
eponychium cuticle
mitosis of cells in stratum basale beneath lunula; 1 in/yr how does growth occur in nails
restoration of normal/near normal function and structure goal of wound healing of the skin
epidermal and deep wound types of wound healing of skin
epidermal wound healing example abrasions and minor burns
epidermal wound healing process basal cell moves into wounded area and enlarges; migration continues until wound is resurfaced, contact inhibition stops migration; cells form new strata
EGF connection Epidermal growth factor stimulates growth of epidermal cells and fibroblasts
Deep wound healing example injury to dermis and subcutaneous layer
inflammatory, migratory, proliferative, maturation deep wound healing phases
inflammatory phase vascular/cellular response; blood clot forms; WBCs migrate to destroy invading microorganisms
Migratory phase scab forms, epidermal cells migrate beneath scab to bridge wound; fibroblasts form scar tissue; granulation tissue forms
proliferative phase extensive growth of epidermal cells; collagen deposited
maturation phase scab sloughs off; epidermal cells are replaced toward original thickness; collagen fibers organize
Created by: auweb921
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