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bio 240 units 0 + 1

TermDefinition
triglycerides glycerol + 3 fatty acids which function as long - term storage in adipose connective tissue, structural support, cushioning, insulation
phospholipids glycerol, 2 fatty acids, a phosphate group, and various organic groups which make up plasma membrane
steroids 4 rings composed predominantly of hydrocarbons that differ in side chains extending from the rings functioning for cholestrol, hormones, and formation of micelle in digestion
eicosanoids 20 carbon fatty acids acting as local signaling molecules in all body systems
glycogenesis when blood glucose levels drop between meals, glycogen is hydrolyzed and released into blood
passive transport transport process that does NOT require energy because it goes ALONG concentration gradient (goes from HIGH to LOW)
active transport transport process that DOES require energy because it goes AGAINST concentration gradient (from LOW to HIGH)
simple diffusion movement of small nonpolar molecules across membrane unassisted as it is unregulated by concentration gradient
facilitated diffusion occurs when small solutes are blocked from passing through plasma membrane by membrane
aquaporins integral protein water channels used to alter the amount of water crossing the plasma membrane by changing the number of aquaporins
primary active transport uses energy by ATP
secondary active transport uses energy by kinetic energy
interstitial growth long bone's growth in length
appositional growth bone's growth in diameter/thickness
zone of resting cartilage cartilage attaches to epiphysis (zone farthest from medullary cavity of diaphysis and closest to epiphysis)
zone of proliferating cartilage rapid mitotic cell division, enlarge slightly, and become aligned in lacunae into longitudinal columns like a stack of coins (2nd zone closest to epiphysis)
zone of hypertonic cartilage chondrocytes stop dividing and enlarge in size (hypertrophy). the walls of lacunae thin out and chondrocytes resorb matrix
zone of calcified cartilage composed of 2-3 layers of chondrocytes. minerals are deposited in the matrix between columns of lacunae. the calcification limits nutrient diffusion which causes destruction of chondrocytes + makes matrix opaque
zone of ossification walls break down and longitudinal channels are formed. osteoprogenitor cells are developed into osteoblast cells. (zone farthest from epiphysis and closest to meduallary cavity
osteoprogenitor cells cells that differentiate into osteoblasts
osteoblasts specialized cells responsible for creating new bone tissue and repairing skeletal damage
osteocytes cells derived from osteoblasts responsible for making up 90 - 95% of adult bone formation
osteoclasts specialized multi-nucleated giant cells that break down and resorb tissue to support growth, repair, and remodeling
mechanical stress (load) happens in the form of weight - bearing movement exercise
growth hormone stimulates liver to produce insulin growth factors which causes cartilage proliferation at epiphyseal plate + bone elongation
thyroid hormone stimulates bone growth supporting metabolic rate of osteoblasts
calcitonin promotes calcium deposition in bone + inhibits osteoblast activity (has minimal effects in adulthood)
sex hormones stimulates osteoblasts + promotes epiphyseal plate growth / closure
parathyroid hormone increases blood calcium levels by encouraging bone resorption by osteoclasts
calcitriol increases blood calcium levels by encouraging bone resorption by osteoclasts + stimulating absorption of calcium ions from the small intestine into the blood
glucocorticoids increase bone loss (in children it impairs bone growth in response to chronically high levels of glucocorticoids)
serotonin inhibits osteoprogenitor cells from differentiating osteoblasts
hematopoiesis formation and development of blood cells
calcium essential mineral for such body functions like muscle contraction and blood clotting
phosphate structural component of ATP, nucleotides, and phospholipids
diaphysis the shaft/central portion of bone
medullary cavity cylindrical space within diaphysis
proximal epiphysis the end of long bone closest to bone trunk
distal epiphysis end of long bone farthest from the trunk of bone
articular cartilage thin layer of hyaline cartilage covering the join surface of epiphysis
metaphysis region of long bone where the widen and transfers forces between diaphysis and epiphysis
epiphyseal line remnant of epiphyseal plate that remains when long bone growth ceases (thin and defined area of compact bone)
periosteum thick and fibrous membrane covering external surface of bone except for articular cartilage on epiphysis
perforating fibers the collagen fibers anchoring the periosteum to bone
endosteum layer of cells lining the inner surface of bone in medullary cavity
bone vascularization having many blood vessels
nutrient formation only one nutrient artery enters and one nutrient vein exits the bone via a small opening or hole
red bone marrow contains connective tissue, developing blood cells, and adipocytes
yellow bone marrow fatty substance which fills medullary cavity of long bones + epiphyseal inner cores
anterograde transport the movement of materials from the cell body toward synaptic knobs
retrograde transport the movement of materials from synaptic knobs toward cell body
fast axonal transport a type of retrograde transport mechanism that involves along mictrotubules
slow axonal transport movement that results from the flow of the axoplasm
multipolar neuron multiple processes extend directly from the cell body (many dendrites and one axon) - most common type of neuron
bipolar neuron two processes extend directly from the cell body (one dendrite and one axon)
unipolar neuron single short process that extends directly from the cell body and is shaped like a T as a result of the fusion of two processes into one long axon
anaxonic neuron processes that are only dendrites (just the dendrites and cell body, no axon)
sensory neuron (afferent) neurons of the sensory nervous system responsible for relaying sensory input from either somatic sensory or visceral sensory receptors towards the CNS (axon of sensory neurons are within sensory nerves and mixed nerves) - most sensory neurons are unipolar
motor neurons (efferent) neurons of the motor nervous system responsible for relaying motor output away from the CNS to both somatic and autonomic (visceral) effectors
interneurons (association) located entirely within the CNS - they receive sensory input from sensory neurons and initiate motor output to motor neurons
glial cells nervous system cells that support neurons
astrocytes most abundant glial cells in the CNS which function in helping the blood brain barrier, regulate interstitial fluid composition, form structural support, assist in neuronal development, alter synaptic activity, and occupy the space of dying neurons
ependymal relates to the cellular lining of brain ventricles and central canal of the spinal cord (also assists in production + circulation of CSF (cerebrospinal fluid))
microglia category of small glial cells in the CNS which wander and exhibit phagocytic activity
oligodendrocytes a type of glial cells in the CNS that wrap around and insulate the axons
satellite cells flattened cells arranged around neuronal cell bodies in a ganglion
neurolemmocytes (Schwann cells) elongated and flattened cells that wrap around and insulate axons within the PNS to form a myelin sheath through MYELINATION
myelin the insulating covering around the axon that consists of repeating concentric layers of plasma membrane of glial cells
myelination the process by which part of an axon is wrapped with myelin
neurilemma used to describe the thin rim of cytoplasm and nucleus on the periphery of a neurolemmocyte
neurofibril the filamentous protein structure in a neuron composed of neurofilaments that form gaps between neurolemmocytes
unmyelinated axons unmyelinated axons associated with neurolemmocytes to help protect and support the axon
multiple sclerosis autoimmune disorder in which there is progressive demyelination of neurons
Guillain Barre syndrome autoimmune disorder due to inflammation that causes the loss of myelin surrounding neurons
neurotransmitter chemical released from a neuron that binds to receptors of another cell to initiate a cellular change
acetylcholine neurotransmitter produced by the CNS and PNS
biogenic amines derived from certain amino acids by the removal of a carboxyl group and the addition of another functional group by enzymatic pathways within the cytosol of a neuron
neuromodulation the release of chemicals from cells that locally regulate or alter the response of neurons to neurotransmitters
Created by: caroline d'silva
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