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cellbio 4 3
transcription + control factors
| Term | Definition |
|---|---|
| translation | rna converted to amino acids in ribosome |
| codon | 3 nucleotides that code for 1 amino acid |
| a-site | mRNA enters and tRNA reads codons |
| p-site | proteins are built from amino acids |
| e-site | ribosome lets go of mRNA |
| mutagens | substances that increase chance of mutation |
| substitution error | nitrogen base on nucleotide is translated wrong |
| silent mutation | sub error doesnt change what protein is made |
| missense mutation | sub error gives wrong amino acid |
| nonsense mutation | sub error gives STOP codon too early, protein useless |
| frameshift error | codon incorrectly added/deleted, shifts entire rna strand to be read wrong |
| constitutional genes | what every cell does |
| relative genes | turned on/off in different types of cells |
| operons (bacteria) | master switch to turn on/off multiple genes |
| repressible operons | default is on |
| trip operon | turns off if theres tryptophan to eat. otherwise bacteria makes its own |
| inducuble operons | default is off |
| lac operon | only turns on if there's lactose to eat |
| dne methylation | put methyl group before gene if you want it off |
| histone | protein core dna is wrapped around. genes you dont want read are towards center/harder to reach |
| acetal groups | increase change of gene expression |
| methyl groups | decrease change of gene expression |
| transcription factors | make it easier for dna polymerase to bind |
| poly-A tails | longer tail = gene active longer, vice versa |
| alternative splicing | keeping/removing means you get different proteins from same gene |