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cellbio 4 1
history + dna structure
| Term | Definition |
|---|---|
| Dr. Miescher | war, saved pus bandages to study, discovered cells |
| Dr. Griffith | trying to make pneumonia vaccine, discovered smooth/rough pneumonia |
| smooth pneumonia | kills you dead, dead smooth + live rough still kills you |
| rough pneumonia | harmless |
| Dr. Avery | discovered enzymes, proteases/nucleases, mixed with smooth/rough pneu |
| nuclease | break down nucleic acids |
| protease | break down proteins |
| dead smooth + live rough + nucleases | nucleic acids are control center |
| dna ladder legs | phosphate sugars |
| dna ladder rungs | nitrogen base pairs |
| purines | adenine and guanine, larger/double-ringed |
| pyrimidines | thymine and cytosine, smaller/single-ringed |
| adenine/thymine | 2 places for H to bind |
| guanine/cytosine | 3 places for H to bind |
| dna helicase | unzips dna to make 2 half ladders |
| dna polymerase | turns 2 half ladders into 2 full ladders |
| semi-conservative replication | 1 dna strand into 2- each is half old half new |
| P53 | checks if everything is copied correctly |
| nucleotides | phosphate group and a nitrogen base |
| 5 prime sites | where a nucleotide attaches to another |
| 3 prime sites | where a nucleotide is attached to by another |
| replication forks | where helicase unzips a chunk before moving on to next fork |
| okazaki fragments | bottom rung copied in smaller fragments because of anti-parallel |
| topoisomerase | relaxes coil so helicase can get up in ther |
| single-stranded binding proteins | keeps dna open cause it wants to shut itself so bad |
| primase | helps polymerase attach |
| ligase | sticks okazaki fragments back together |