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Nursing 211

Immune system/Inflammation

What is an innumodeficiency? Infection or malignant disease or both.
What is a hyperimmune activity? Autoimmune disease or hypersensitivity.
Does bone marrow produce differentiated or undifferentiated stem cells? undifferentiated
The maturational pathway of the undifferentiated stem cell depends on what? Body need and the presence of hormones
How does the presence of hormones (cytokines/poietins) affect undifferentiated stem cells? It goes directly to stem cells and tell them what to become based on body needs.
what kind of response is inflammation? Non-specific (Same response for all triggers)
Can inflammation occur without infection? Yes.
Does inflammation provide immediate, short term protection? Yes.
what are 3 purposes of inflammation? 1. Get rid of harmful microorganisms. 2. Cause visible/uncomfortable symptoms 3. stimulate AMI/CMI activation.
What are the 4 cells involved in inflammation? Neutrophils, macrophages, eosinophils, basophils.
Which cell is the first line of defense in inflammation? Neutrophil
which cell in inflammation is big and phagocytic? macrophage
What are immature neutrophils called ? Bands
Why do neutrophils have such a short life span? Once they go through phagocytosis, they lose their energy and die.
what is the function of neutrophils? It's grnaules contain enzymes used to degrade invading organisms.
What is Stage I of inflammation? Changes in blood vessels. initially constriction, then hyperemia and edema d/t effects of histamine and kinins.
What does histamine do in inflammatory repsonse? Causes swelling.
What do kinins do? Cause pain at the site.
What is Stage II in the inflammatory process? Fomation of exudate. (Dead microorganisms/neutrophils)
What is Stage III in inflammatory process? Tissue repair and replacement.
Created by: ctwirler12