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Integument 1

For quiz 1 Path 2

QuestionAnswer
Epidermal layers Surface to deep Corneum, lucidum, granulosum, spinosum, basale. Come, lets, get, sun, burned
Where do you find stratum lucidum On hairless parts of body
Histyocytoma From langerhan cells, usually go away on their own
Cells in epidermis Melanocytes, langerhans, merkel cells
Functions of dermis Tensile strength and elasticity, vascular supply
Hair growth cycle order Anagen-> catagen -> telogen ->return to anagen -> early anagen
Early anagen germ cells in hair bulb proliferate
Anagen New hair grows
Catagen Growth stops
Telogen Mature hair
Exogen hair falls out
Sebaceous gland Secretes sebum
Sweat gland Eocrine Tubular, secrete onto epidermal surface
Sweat gland Apocrine Coiled, secrete at follicular ostia
Portals of entry for epidermis Absorption, penetrating trauma, UV exposure, Direct contact with irritant, extreme temperatures, hematogenous, nerves, through follicle
Erysipelothrix rhusiopathiae Diamond skin, hematogenous spread
Feline Herpes 1 Nerve, ulcerative facial dermatitis
Demodex Live in hair
Hyperkaratosis Increased thickness in strat corneum
Two types of Hyperkaratosis Orthokeratosis and Parakeratosis
Difference between the two types of hyperkeratosis? Orthokeratosis has no nuclei present, parakaratosis has nuclei. O as in NO, Paranormal cause parakara is abnormal
Zinc responsive dermatosis Parakeratosis, nutritional
Hepatocutaneous syndrome Parakeratosis, disease
Lupus Erythematosus Apoptosis of keratinocytes
Edema Intercellular (Spongiosis)- secondary to trauma or acute inflamm
Hydropic/ Balloning Intracellular- cytoplasmic swelling. Has viral inclusions
Acantholysis Immune mediated injury and occasionally pyoderma, disruption of intercellular attachments
Vesicle Less than 1 cm
Bulla Greater than 1 cm
Ruptured vesicle can lead to Erosion
Crust Dried fluid and cellular debris
Rain rot Dermatophilus congolensis
If you see a chain of cocci from a crust sample, what disease could this be? Rain rot
Normal increased melanin production Lentigo (orange cats)
Rare cause of hyperpigmentation Increased # of melanocytes
Lichenification Hyperpigmentation with hyperkeratosis due to chronic self-trauma
Hypopigmentation Albinism- congenital or hereditary mutation. Aquired- nutrition (copper), trauma, Immune mediated, or age related
Leukotricha Unknown cause of loss of pigment (Pretty dog
What can occur in cats with hyperadrenocorticism? Skin fragility syndrome
Two phases of fibrosis Phase 1: Granulation tissue, Phase 2: Scar formation
What can occur in a horse with excess granulation tissue Proud flesh
Mucin GAG accumulation -> myxedema (high affinity for water) Looks like Shar pei dog
What can cause myxedema Hyperthyroidism
4 types of mineral accumulation in skin dystrophic, metastatic, iatrogenic, and idoipathic
Acute dermatitis Less than 3 days, hyperemia, edema, fibrin, neutrophils
Acute dermatitis can result in 3 outcomes Complete resolution, resolution with scar, and progression
Chronic dermatitis 2 weeks, macrophages, lymphocytes, plasma cells, abscesses. Fibrosis-> scaring
Acral lick dermatitis hypertrophy of hair follicles
Folliculitis inflammation of hair follicle
Perifolliculitis Around follicle
Mural folliculitis Within wall
Luminal folliculitis within follicle lumen
Furunculosis Hair follicle rupture
Hidradenitis Inflammation of apocrine sweat gland
Sebaceous adenitis Inflammation of sebaceous gland, usually seen in poodle or akita
How do you diagnose Sebaceous adenitis Skin biopsy
Panniculitis Inflammation of subcuticular adipose tissue, looks like lots of bumps under skin
Created by: user-2000257
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