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Anes Def

Anesthesia definitions

QuestionAnswerExplanationsRef
Name the state or ability to perceive, to feel, or to be conscious Awareness Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
Name a type of memory in which conscious recall of specific facts and events Explicit Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
Name a type of memory in which previous experiences aid without conscious awareness of these previous experiences Implicit capable of being understood from something else though unexpressed; Latin implicitus involved, obscure, variant past participle of implicāre Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
Process whereby exposure to a stimulus influences response to a subsequent(later) stimulus Priming Priming is the implicit memory effect Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
State in which information from surroundings can be processed Consciousness Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
Ability to retrieve stored memories Recall Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
Absence of recall; a condition in which one's memory is lost Amnesia Event not retained in long-term memory Robins K et al. Intraoperative Awareness During General Anesthesia for Cesarean Delivery Anesth Analg, 109:886-890, 2009
Pharmacogenetic disorder in which anesthetics trigger a sustained increase in intramyoplasmic Ca2+ that leads to hypermetabolism, muscle rigidity, rhabdomyolysis, and death Malignant Hyperthermia (MH) autosomal dominant inheritance Nelson TE. Malignant hyperthermia: a pharmacogenetic disease of Ca++ regulating proteins. Curr Mol Med 2002;2:347–69
Specific treatment for MH Dantrolene Dantrolene sodium is the only drug effective for treatment of Malignant hyperthermia Anesth Analg 2010;111:1400 –10
The most common site of mutations in MH Ryanodine receptor (RYR1) for the skeletal muscle intracellular Ca2+ release channel. It is not yet feasible to screen the entire population for RYR1 mutations because more than 170 variants, of which 29 are known causative mutations Robinson R, Carpenter D, Shaw MA, Halsall J, Hopkins P. Mutations in RYR1 in malignant hyperthermia and central core disease. Hum Mutat 2006;27:977–89
MH susceptibility conferring in North America by which test? Caffeine-Halothane Contracture Test positive live muscle biopsy(CHCT)or in vitro contracture test (IVCT) in Europe
A class of inherited skeletal muscle diseases characterized by impaired relaxation after sudden, voluntary muscle contraction Myotonias result from skeletal muscle membrane hyperexcitability, inappropriate firing, delay in muscle relaxation, and resultant contracture states of varying severity and duration
Created by: rusam