Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Jaundice
Pediatrics
| Question | Answer |
|---|---|
| __% of infants develop jaundice in the 1st week | 65 |
| Jaundice that appears on days 2-3 and disappears by day 7 (day 14 if premature) is called: | Physiologic jaundice |
| __ fed babies are at higher risk for physiologic jaundice | Breast |
| Jaundice with bilirubin >5mg/dL | Clinical jaundice |
| What is the bodily progression of jaundice | Cephalocaudal: starts at the head and moves down |
| In elevated conjugated bilirubin, suspect: | biliary atresia |
| Unconjugated hyperbilirubinemia that results from increase in RBC destruction (antibody mediated hemolysis) is Coombs: | positive |
| Non-immune hemolysis is Coombs: | Negative |
| How does phototherapy work for unconjugated hyperbilirubinemia? | Unconjugated bilirubin in skin is converted to water soluble isomers that are excreted without conjugation |
| Risks for physiologic jaundice | Preterm. Affected sibling. Asian > white > AA. Breastfeeding-associated jaundice is common. Tx = phototherapy |
| Pathologic unconjugated bilirubinemia: causes related to increased production: | Increased RBC destruction due to antibody-mediated hemolysis (ABO or Rh incompatibility). Nonimmune (hereditary spherocytosis, G6PD, cephalohematoma, polycythemia, ileus ). |
| Pathologic unconjugated bilirubinemia: causes related to decreased conjugation rate | UDPGT deficiency. Crigler-Najar syndrome. Gilbert syndrome. |
| Gives a direct reaction in the van den Bergh test: | Conjugated bilirubin |
| Can cross placenta & is conjugated by mom’s enzymes | indirect/unconjugated bili |
| Water-soluble; placenta is impermeable to: | Direct/conjugated bili |
| Serious, rare, permanent deficiency of glucuronosyltransferase that results in severe indirect hyperbilirubinemia | Crigler-Najjar syndrome |
| Unconjugated bili without hemolysis (usually ≤20 mg/dL) is likely to be due to: | Breast milk jaundice |
| Jaundice >2 wks after birth = | Pathologic; probably direct bilirubinemia (DBil >2 or >20% of TBil) |
| Begin phototherapy when indirect bili = | 16-18 mg/dL |
| Conjugated hyperbilirubinemia is always: | pathologic |
| Jaundice involving the face: total serum bili is approximately: | 5 mg/dL |
| Jaundice involving the abdomen: total serum bili is approximately: | 15 mg/dL |
| Jaundice involving the feet: total serum bili is approximately: | 20 mg/dL |
Created by:
Abarnard
Popular Medical sets