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Nervous System
Anatomy & Physiology - Nervous System Review
| Question | Answer |
|---|---|
| What are the parts of a neuron? | Cell body, Axon, Dendrites |
| What are the functions of a neuron? | Receive signals, process signal information, send signals. |
| What are the 3 types of neurons? How are they structured? | Sensory Neurons - Pseudounipolar Motor Neurons - Multipolar Association Neurons - Multipolar |
| What conveys information from a receptor to the CNS? | Sensory (afferent) neurons |
| What conveys information from the CNS to an effector? | Motor (efferent) neurons |
| What neuron is located entirely in the CNS and is between the previous two? | Association (inter) neurons |
| What is a group of cell bodies in the CNS called? | Nuclei |
| What is a group of cell bodies in the PNS called? | Ganglia |
| What is a bundle of axons in the CNS called? | Tract |
| What is a bundle of axons in the PNS called? | Nerve |
| What are the supporting cells in the CNS? | Oligodendrocytes, microglia, astrocytes, ependymal cells. |
| What is the function of oligodendrocytes? | Spiderman - shooting out extensions of myelin to wrap around the axons. One oligodendrocyte can myelinate many axons. |
| What is the function of microglia? | Pac-Man - get rid of anything that could damage a neuron |
| What is the function of astrocytes? | Sticky hand - regulate the external environment of the neuron. Extensions with "end-feet" - connect capillary and the neuron. |
| What is the function of ependymal cells? | Sober friend of drunk neurons - secretes fluid that protects. |
| What are the supporting cells in the PNS? | Schwann cells, Satellite cells |
| What is the function of Schwann cells? | Wrapping around PNS axons to myelinate them. |
| What is the function of satellite cells? | Support neuron cell bodies in the ganglia of PNS. |
| What are the events of an action potential? | Depolarization, Repolarization, Hyperpolarization |
| What is resting membrane potential? Why is this value important? | -70 mV - high potassium inside - high sodium outside |
| What is threshold? | -55 mV |
| What happens during depolarization? | High potassium inside High sodium outside Threshold reached - voltage regulated Na signals open. -55mV -> 30mV |
| What happens during repolarization? | High potassium AND sodium inside voltage regulated Na channels close and K channels open 30mV -> -100mV |
| What happens during hyperpolarization? | High sodium inside High potassium outside Na/K pump starts: K in - Na out -100mV -> -70mV |
| How is an action potential passed down an axon in only one direction? | Absolute refractory period. You cannot start something that is currently going so when leaking backwards it does not affect anything. |
| What is absolute refractory period? | When the axon cannot further respond to a stimuli because it is already stimulated. |
| What is relative refractory period? | When the axon can be stimulated again but it will not properly work because the ions are in opposite places. |
| What is continuous conduction? | Non-myelinated axons so it has to pass through each part of the axon. |
| What is saltatory conduction? | Myelinated axon so it only has to pass though the nodes of ranvier. |
| Why is myelin important? | It speeds up reactions. |
| What is the All-or-None principle? | The stimulus is either strong enough to cause depolarization or it's not. |
| How do you increase the strength of the response of a nerve stimulus? | Higher frequency or higher number of neurons stimulating. |
| What happens at the synapse when the strength of the nerve stimulus is increased? | |
| What is synapse? | Where neurons communicate. |
| What is the presynaptic neuron? | The neuron sending a signal. |
| What is the synaptic cleft? | Interstitial fluid between the presynaptic and postsynaptic neurons. |
| What is the postsynaptic neuron? | The neuron receiving the signal. |
| What is the series of events that happens at the synapse? | Nerve impulse end of presynaptic axon > depolarization opens voltage regulated Ca+ channels > increase of Ca+ = synaptic vesicles of neurotransmitters into synaptic cleft > neurotransmitters across the cleft into post synaptic neuron > electrical signal |
| What is EPSP? What does it result in? | Excitatory Post Synaptic Potential Na into neuron - Action potential more likely |
| What is IPSP? What does it result in? | Inhibitory Post Synaptic Potential K out of neuron - Action Potential less likely |
| What causes an IPSP? | The flow of negatively charged ions into postsynaptic cell. |
| What is the most studies neurotransmitter? | Dopamine. |
| What is the most prevalent brain neurotransmitter? | Gamma-aminobutyric acid (GABA) |
| What is a reflex arc? | The natural pathway of reflexes. |
| Describe the elements of a reflex arc. | sensory receptor - reacts to a stimulus sensory neuron - carries message to integration center integration center (CNS) - process info & directs to motor output motor neuron - carries message to effector effector organ - muscle or gland |
| Distinguish between somatic reflexes and autonomic reflexes. | Somatic - reflexes that stimulate skeletal muscle (voluntary) Autonomic - reflexes that stimulate smooth or cardiac muscle (involuntary) |
| What are the three main regions of the cerebrum? | Cortex, white matter and basal nuclei |
| Describe the cortex | Grey matter - cell bodies |
| Describe the white matter | Myelinated axons |
| Describe the basal nuclei | Deep pockets of grey matter(cell bodies) |
| What are the surface lobes of the cerebrum? | Frontal lobe, parietal lobe, occipital lobe, temporal lobe. |
| What is the function of the primary somatic sensory area and where is it located? | Receives impulses from sensory receptors (left side of body - right side of primary somatic sensory area) Located in parietal lobe posterior to central sulcus |
| What is the function of the primary motor area and where is it located? | Sends impulses to skeletal muscle Located in frontal lobe |
| What is the function of the Broca's area and where is it located? | Involved with our ability to speak Located in left hemisphere of the frontal lobe |
| What are the three parts of the diencephalon. | Thalamus, Hypothalamus, Epithalamus |
| What is the function of the thalamus and where is it located? | transfers impulses to the correct part of the cortex surrounds third ventricle relay center for sensory impulses |
| What is the function of hypothalamus and where is it located? | Autonomic nervous system center - regulates metabolism and temperature and controls water balance. Emotions and smell Pituitary gland Under the thalamus |
| What is the function of the epithalamus and where is it located? | Includes the choroid plexus - forms cerebral spinal fluid Houses pineal body - an endocrine gland Forms roof of the third ventricle |
| What are the three parts of the brain stem? | Midbrain, Pons, Medulla oblongata |
| What is the function of the Midbrain? | Information highway |
| What is the function of Pons? | Information highway & breathing control |
| What is the function of the Medulla Oblongata? | Automatic responses |
| What does the Reticular Activating System (RAS) control? | Plays role in awake/sleep cycles and consciousness Filter for incoming sensory information |
| What does the cerebellum control? | Balance and equilibrium Provides precise timing for skeletal muscle activity and coordination of body movements |
| What are the layers that protect the Central Nervous System? | Scalp and skin, skull and vertebral column, meninges, cerebrospinal fluid, blood brain barrier |
| Describe the scalp and skin. | Outer layer of body that protects the inside. |
| Describe the skull and vertebral column. | Boney protection. |
| Describe the meninges. | Arachnoid layer - middle layer, weblike extensions span the subarachnoid space, arachnoid villi reabsorb the cerebrospinal fluid Pia layer - internal layer, clings to the surface of the brain |
| Describe the cerebrospinal fluid (CSF) | A water cushion to protect the brain. Formed by choroid plexus - capillaries in the ventricles of the brain. Circulated in the arachnoid space, ventricles and the central canal of the spinal cord |
| What is the blood brain barrier? | Least permeable membrane capillaries of the body. Keeps many harmful substances out of brain |
| What cannot cross the blood brain barrier? | Metabolic wastes, most drugs, nonessential amino acids, potassium ions |
| What can cross the blood brain barrier? | Water, glucose, essential amino acids, alcohol, nicotine |
| What is a cerebrovascular accident (CVA)? | Stroke. A ruptured blood vessel that supplies a region of the brain. Blood no longer has a source of oxygen. Loss of some functions. |
| Where does the spinal cord originate and end? | The foramen magnum ("hole" in the bottom of the skull) The L1-L2 |
| What is contained in the dorsal root of the spinal cord? | Somatic sensory neurons. |
| What is contained in the ventral root of the spinal cord? | Somatic motor neurons. |
| How many pairs of cranial nerves branch from the surface of the brain? | 12 |
| What is the order of the nerves that exist in the spinal cord? | 8 Cervical (C1-C8) 12 Thoracic (T1-T12) 5 Lumbar (L1-L5) 1 Coccygeal *spinal cord ends at about L1-L2* |
| Distinguish between the Somatic Nervous System and Autonomic Nervous System. | Somatic - voluntary - skeletal muscle Autonomic - involuntary - smooth and cardiac muscle |
| What are the divisions of the Autonomic Nervous System? | Sympathetic and parasympathetic |
| What is the function of the sympathetic autonomic system? | "fight or flight" response to unusual stimulus. The "e" division; exercise, excitement, emergency, embarrassment. |
| What is the function of parasympathetic autonomic system? | "housekeeping" activities - conserve energy, maintain necessary body function. The "d" division; digestion, defecation, diuresis |
| Where do the preganglionic neurons originate in the sympathetic autonomic system? | T1-L2 |
| Where do the preganglionic neurons originate in the parasympathetic autonomic system? | S2-S4 & cranial nerves III, VII, IX, X |
| What neurotransmitters are released in the sympathetic autonomic system? | norepinephrine & epinephrine (effector organs) |
| What neurotransmitters are released in the parasympathetic autonomic system? | acetylcholine |
| What is the function of the visual area and and what cerebral area is involved with it? | Receives, integrates and processes information from the retinas. The occipital lobe |
| What is the function of the auditory area and and what cerebral area is involved with it? | Processing speech and other complex acoustical signals like music. The temporal lobe |
| What is the function of the olfactory area and and what cerebral area is involved with it? | Purely sensory. Carries impulses for the sense of smell. Beneath the frontal lobe |