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Lymphatic System p3
AP 2, Dr. Cutler, GTCC
| Term | Definition |
|---|---|
| What type of receptor complex does the cytotoxic T cell have? | CD 8 |
| What does Major histocompatibility complex (MHC) one means? | -infected -kill me |
| What does major histocompatibility complex (MHC) two mean? | -professional -watch for this "2 fingers -> holder" |
| What badge is worn by T-cells for identification that everyone has? | CD 3 Receptor Complex |
| Helper T-Cells have what type of receptor complex? | CD4 |
| Which property has an active/inactive group, where active fights immediately and inactive fights second time? | memory |
| Which property immune system ignores normal antigens (self-antigens)? | Tolerance |
| Which cells provide cell-mediated immunity against abnormal cells inside cells? | T-Cells |
| What cells provide antibody immunity against antigens in body fluids? | B-cells |
| What type of t-cell "takes out the house", responsible for cell-mediated and enters tissues & directly attack antigens physically and chemically? | Cytotoxic T-cells (TC) |
| What type of t-cell stimulates responses of t-cell and and especially activate b-cells? | Helper T-cell (TH) |
| What type of t-cell is produced and activated if pathogens occur again later? | Memory T-cell |
| What type of t-cell STOP function of t-cells and b-cells when attack should end? | Suppressor T-cell (TS) |
| ______ adaptive: Antibodies are transferred from another source. | Passive |
| What immunity if after birth and develops after exposure to a specific antigen? | Adaptive |
| How do you naturally acquire active immunity? | Environment exposure/ Putting it in your mouth |
| How do you artificially acquire active immunity? | Vaccination |
| How do you naturally acquire passive immunity? | From your mother |
| How do you artificially induce passive immunity? | Injections of antibodies [Human Rabies Immune Globulin] |
| What property where each T or B cell responds only to a specific antigen and ignore all others? | Specificity |
| Which property CLONES active lymphocytes of itself that are sensitive to same antigen at any time to any antigen? | Versatility |
| What type of immunity defends against antigens in the BODY FLUIDS AND TISSUES? | Antibody-mediated (Humoral) |
| ________ adaptive: Antibodies develop due to exposure to antigen. | Active |
| What is known as an antigen that can be used to identify pathogens and shown to t-cells? | Antigen Presentation |
| What marker is found on cytotoxic cells and respond to antigens on class MHC 1 proteins? | CD8 markers "Look in MHC1 to see if it has virus" |
| What marker is found on Helper T-cells and respond to antigens on class MHC2 protein? | CD4 markers "Call 4 help" |
| What class MHC is found in all membranes and mature cytotoxic t-cells respond to it? | MHC 1 "window" |
| What class MHC is found ONLY in antigen-presenting cell membranes and mature helper t-cells respond to it? | MHC Two "Professional" |
| How do CD4 alert APC using MHC2? | 1. Produce battle cytokines 2. Cytotoxic T's & more Macs answer call 3. Activate B cell to divide, making antibodies & memories |
| MHC one antigen presentation causes cytotoxic T's to: | 1. Release perforin 2. Secrete lymphotoxin (granzyme) 3.Causes cell to die from apoptosis |
| What is secreted by active T-Helper cells and an inflammatory response to protein? | Cytokines "siren" |
| What is the over-secretion of cytokines? | Cytokine Storm |
| B-cells - Steps to division. S.A.D. | Sensitization - matching pathogens Activation - permission from helper cells Division - explosion/seperation |
| What B-cell releases histamine in the allergy response? | IgE "Allergy" |
| How antibodies work: O.L.A.F. | Opsonization - safety orange Labels - neon sign "eat this" Antitoxins - block toxins Formation of immune complex - big wed eaten by Macs |
| Which response is faster? Why? | Secondary ; memory cells are already primed |
| What immunity is acquired due to an exposure? | Adaptive (specific) |
| "Unintentional" Encounters | Accidental |
| What type of b-cells fight the first 3-4 days after division? | Plasma B cells |
| What B cell waits until second exposure to fight after division? | Memory B-cells |
| What are the 5 bases of antibodies? | IgG, IgA, IgM, IgE, IgD |
| What time of antigen interacts at an antigen binding site? | Specific |
| Where do the pathogens bind on the antigen? | Epitopes |
| What do epitopes form when they bind to pathogens on the antigen? | Antigen-antibody complex |
| Where are antibodies found? | Body Fluid |
| What determines an antibody? | Constant segments (the base; G.A.M.E.D) |
| What do antibodies have no effect on? | Antibody specificity |
| What is made first in response to blood transfusion reaction causing clumping/agglutination? | IgM "Antibodies" |
| What B-cell is most common long-term and 80% of all antibody? | IgG "RhAntibodies" |
| "Intentional" exposure | Vaccines |
| What immunity remembers different pathogens & takes appropriate action? | Adaptive |
| What do B-cells, T-cells and antibodies respond to? | Antigens |
| Cell-mediated immunity are led by ________ cells? | T-cells |
| What type immunity is led by t-cells and uses perforin and granzymes? | cell-mediated |
| What type of immunity is directed by B-cells and uses antibodies? | Anti-body mediated (Humoral) |
| What defends against abnormals cells and pathogens INSIDE CELLS? | cell-mediated immunity |
Created by:
Angiee0412
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