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serology
MT
Question | Answer |
---|---|
Fimbriae | Structures that arise near the plasma membrane and project through the cell wall |
Protein found in association with the hyluronic capsule | M-Protein |
Streptolysin O (SLO) | Oxygen liable enzyme, binds to sterols in the red blood cell membrane |
Oxygen-stable enzyme is responsible for beta hemolysis on a blood agar plate | Streptoysin S |
Spreading factor,braks down hyaluronic acid found in host tissue | Hyaluronidase |
Streptokinase | an enzyme that dissolves clots by turning plasminogen to plasma |
elaborated by scarlet fever and shows a rash | Erythrogenic Toxin |
S.Pyogenes | Causes infections in upper respiratory system and strep throat |
ASO and Anti-DNase B | Are used for titers for S pyogenes |
Superantigens | Are capable of binding to alpha/beta T-cell receptors |
S. Agalactiae | Serious disease in adults and neonates |
Syphilis is caused by | Spirochete |
What is transmitted by sexual contact in humans | Treponema Pallidum |
What happens to progressions of untreated syphillis | divided into stages |
Classic serologic test for syphillis measure the antibody--2 types | Treponemal-nontreponemal |
Lyme disease | caused by a spirochete bacterium or a hard body tick called Borrelia burgdorferi |
Unique exspanding skin lesion,tick bite to human skin | (EM) Erythema migrans |
What does Lyme borreliosis affects, what type of body parts | Skin,nervous system,heart and joints |
Most common labboratory assays for B.Burgdorferi for antibody detection are | IFA,ELISA,PreVue |
OspA and OspB are proteins from bacterial outer wall from what | B Burgdorferi |
Ehrlichiosis | general term for both anaplasmosis and HME |
Possibly a fatal tick borne disease | Babesia |
A mosquito-borne virus present in the US | West nile Virus |
West nile Virus is detected by | RT-PCR |
Birds and mamals, undercooked raw meat | Toxoplasma gondi |
Definite host of toxoplasma gondi | House cat |
What test is used for the detection of T.Gondi | ELISA |
CMV---Cytomegalovirus | member of the herpes virus |
Most common virus transmitted to the fetus | CMV |
CID | may be fatal, can cause permanent neurologic sequelae |
CMV can be transferred in 2 ways | Transfussion of fresh blood or organ transplant |
CMV is a major cause of | congenenital viral infections |
A human herpesvirus | EBV |
This virus causes complications such as cardiac,ocular,respiratory,hematologic,digestive,renal, and neurologic systems. | EBV |
The guinea pig kidney contains what type of antigen | Forssman antigen |
What is the cause of monnucleosis | EBV virus |
The EBV can be a major concern for what type of individuals | Immunocompromised patients |
What antibodies are present in infectious mononucleosis | Heterophil and EBV antibodies |
Inflammation of the liver is | Hepatitis |
Four phases of acute hepatitis | Incubation,preicteric,icteric and convalescence |
If a patient is HBsAg and Anti-HBc positive, this means | Chronically infected |
Pharyngitis,Scarlet fever, and Impetigo are causes from what | S.Pyogenes |
Hyaluronidase | Also called spreading factor |
Dissolves clots by converting plasminogen into plasma | Streptokinase |
Responnsible for characteristics scarlet fever rash | Erythrogenic toxin |
S.pyogenes is usually | Beta hemolytic |
Provides specific immunity,inhibits phagocytosis and found w/hyaluronic capsule | M-protein |
hyalurondase,D-nase and Erythrogenic toxin is produced by what | S.pyogenes |
Presence of betalipoprotein,bac contamination and shaking of a reagent causes | False ASO reults |
Long term complications of S.pyogenes are from | R.fever and poststrep |
Proteolytic enzymes causes | Necrotizing fasciitis |
Highest reported levels of sensitivity testing for Gr.A strep are | Surface/optical immunassay |
Diagnosis of strep and ASO cannot be used,whats next | Anti -D-NAse-B |
Hutchinson teeth is called | Congenital syphilis |
Syphillis is to | Trep. Pallidium |
Bejel is to | T.Pallidum |
Nontreponal antibodies produce by a infected person is caleed | Reagin antibodies |
FTA-ABS test and MHA-TP test are | Treponemal method |
Nontreponemal method | RPR test |
Infectious.Monoucleosis,leprosy and R.arthritis can cause a false pos on what test | RPR procedure |
Treponema pallidium blood in 4C last how long | 3 days |
How long is the incubation period for Syphillis | 3 weeks |
The serologic method of syphillis is called what phase | Latent phase |
Ixodes pacificus,I.scapularis and I.ricinus creats what | Lyme disease |
What test is used to distinquish between true pos and false pos | PCR-Polymerse chain reaction |
Symptoms of lyme meningitis is | Severe headache and siff neck. |
Retinal detachment,loss of vision and cranial nerve palsies are caused by | Lyme disease |
Flagellar 41 KD polypeptide is fisrt reponse from what antigen | B.Burgdorferi |
Ehrlichia species are also known for | Rocky mountain spotted fever |
Babesiosis is caused by | Babesia microti |
Where can you find Babesiosis organism in the body | Peripheral blood |
Parasitic infection is caused by | Toxoplasmosis |
The host for T-gondii is | Domestic cat |
What descibes CMV | Herpes, DNA virus and cell associated virus |
Cell associated viruses is similar to | herpesvirus |
What common way would you attract the CMV virus | Venereal route |
VCA means | Viral CApsid antigen |
EBV can cause what diseases | monoucleosis,lymphoma and carcinoma |
What is the mode of transmission of EBV | Oral secretions |
B-type,capsid antigen and early antigen are characteristics of | EBV infected lymphocytes |
Infectious monoucleosis has no | acute stage |
Paul bunnell screening test uses | sheep erthrocytes |
Davidson diff test screening test uses | beef erythrocytes |
Monoslide agglutination test uses | horse erythrocytes |