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Integumentary

The Integumentary System

QuestionAnswer
What is the hypodermis? The subcutaneous tissue just deep to the skin. It is also called the superficial fascia because it is superficial to the tough connective tissue wrapping of the skeletal muscles.
What does the hypodermis do? Stores fat. anchors the skin to the underlying structures (mostly to muscles). acts as a shock absorber. insulates heat.
What is the epidermis? the outermost protective shield of the body. it is keratinizes stratified squamous epithelium. has 4 cell types and 5 layers.
What are keratinocytes? most epidermal cells are keratinocytes. produce keratin.
What is keratin? the fibrous protein that helps give the epidermis its protective properties.
What is a callus? persistent friction that causes a thickening of the epidermis.
What are melanocytes? the spider-shaped epithelial cells that synthesize the pigment melanin.
What is melanin? the melanin granules accumulate on the superficial or "sunny" side of the keratinocyte nucleus, forming a pigment shield that protects the nucleus from the damaging effects of UV radiation in sunlight.
What is the function of epidermal dendritic cells? the ingest foreign substances and are key activators of our immune system. their slender processes extend among the surrounding keratinocytes, forming a more or less continuous network.
What is thermoregulation? the homeostatic regulation of body temperature
What are the two major components of the integumentary system? skin (cutaneous membrane) and its accessory structures located primarily in the dermis (hair and nails) and various glands,muscles and nerves.
What are some functions of the integumentary system? -guards the physical & biochemical integrity of the body. -maintain a constant temperature. -provide sensory info about the surrounding environment. -metabolism.
What is thermoregulation? the homeostatic regulation of body temperature.
What is the largest organ of the body? the skin. it is made up of different tissues joined to perform specific functions.
What are langerhans cells? epidermal dendritic cells. -arise from red bone marrow and migrate to the epidermis. -participate in immune responses against microbes that invade the skin.
What are tactile (merkel) cells? They are located in the deepest layer of the epidermis. -they contact the flattened process of a sensory neuron.
What is the stratum germinativum(basale)? deepest layer of epidermis.-forms the epidermal ridges which extend into the dermis and are adjacent to the dermal papillae which extend into the epidermis.
What cells make up the stratum germinativum? single row of cubodial or columnar keratinocytes. they are the youngest keratinocytes. nuclei are large in this layer. melanocytes and tactile cells are also found here.
What is the stratum spinosum? 2nd deepest layer. The prickly layer. 8 to 10 layers of polyhedral keratinocytes bound together by desmosomes.
What cells are found in the stratum spinosum? cells in the more superficial portions of this layer become flattened as they produce more and more keratin filaments.
What is the stratum granulosum? middle layer. the granular layer. 3 to 5 layers of flattened keratinocytes that are undergoing apoptosis. the nuclei of these celss begin to degenerate and eventually die.
What are keratohyalin granules? found in the stratum granulosum. they help form keratin in the upper layers. and help with dehydration of cells.
What are lamellar granules? membrane enclosed granules found in the stratum granulosum. they release a lipid rich secretion that fills the spaces between cells of this layer and between more supeficial cells of the epidermis.
What do the lipid rich secretions of lamellar granules do? it is a water repellent sealant that retards loss of body fluids and entry of foreign materials.
What is the stratum lucidum? the 2 layer closest to the outside of the body. the clear layer. present only in skin of fingertips, palms and soles. (thick skin) 3 to 5 layers.
What cells are in the stratum lucidum? 3 to 5 layers of clear, flat, keratinocytes without a nucleus or organelles filled with eleidin(an intermediate in the synthesis of keratin).
What is the stratum corneum? 25 to 30 layers of dead, flatted keratinocytes. the horny layer. these cells are continuously shed and replaced by cells from deeper stratum. water resistant but not waterproof.
What is the stratum spinosum? 2nd deepest layer. The prickly layer. 8 to 10 layers of polyhedral keratinocytes bound together by desmosomes.
What cells are found in the stratum spinosum? cells in the more superficial portions of this layer become flattened as they produce more and more keratin filaments.
What is the stratum granulosum? middle layer. the granular layer. 3 to 5 layers of flattened keratinocytes that are undergoing apoptosis. the nuclei of these celss begin to degenerate and eventually die.
What are keratohyalin granules? found in the stratum granulosum. they help form keratin in the upper layers. and help with dehydration of cells.
What are lamellar granules? membrane enclosed granules found in the stratum granulosum. they release a lipid rich secretion that fills the spaces between cells of this layer and between more supeficial cells of the epidermis.
What do the lipid rich secretions of lamellar granules do? it is a water repellent sealant that retards loss of body fluids and entry of foreign materials.
What is the stratum lucidum? the 2 layer closest to the outside of the body. the clear layer. present only in skin of fingertips, palms and soles. (thick skin) 3 to 5 layers.
What cells are in the stratum lucidum? 3 to 5 layers of clear, flat, keratinocytes without a nucleus or organelles filled with eleidin(an intermediate in the synthesis of keratin).
What is the stratum corneum? 25 to 30 layers of dead, flatted keratinocytes. the horny layer. these cells are continuously shed and replaced by cells from deeper stratum. water resistant but not waterproof.
What is the calcitriol? the active form of vitamin D which is required for normal absorption of calcium and phosphorus by the small intestine.
What is the dermis? deeper, thicker layer made-up of connective tissue containing collagen and elastic fibers.
What cells are present in the dermis? fibroblasts, macrophages, adipocytes.
What is the papillary layer? first layer of the dermis. consists of areolar CT containing fine elastic fibers.
Created by: emilylueanng
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