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inflammation
final patho
| Term | Definition |
|---|---|
| inflammation | body response to injury and is mediated by immune system; defense response in attempt to heal and repair |
| purpose of inflammtion | neutralize the antigen and heal injury |
| Acute inflammation | resolves when invader is gone; compete healing by connective tissue |
| Chronic inflammation | persistent inflammation for long period of time |
| chronic inflammation can lead to what | asthma, COPD, DM |
| causes of inflammation | trauma, foreign bodies, burns, infection, allergy response, ischemia |
| s/s of inflammation | Erythema (red skin), edema, heat, pain, loss of function |
| phagocytosis | when WBC's travel to injury site and consume invaders |
| Cirrhosis | irreversible inflammatory fibrotic liver disease; infiltration of leukocytes; NO CURE |
| Patho of cirrhosis | liver takes on cobbly appearance, liver become larger or smaller and harder to palpate |
| cirrhosis disease progression | healthy liver-> fatty liver-> liver fibrosis (scar tissue)-> cirrhosis= irreversible liver damage |
| Causes of cirrhosis | viral/parasitic infection, hep a-b-c, nonalcoholic fatty liver disease, biliary cirrhosis, alpha I antitrypsin deficiency |
| s/s of cirrhosis | easy bruising/bleeding, esophageal varices, jaundice, pruritis, asterixis (muscle tremor), edema, spider nevi, slurred speech, caput medusa |
| What is the gold standard to diagnose cirrhosis | Liver biopsy |
| rheumatoid arthritis | autoimmune condition, deterioration of connective tissue |
| Three processes in RA | 1. Neutrophils & other cells in the synovial fluid become activated 2. Inflammatory cytokines: induce enzymatic breakdown of cartilage & bone 3. T cells also interact w/ synovial fibroblasts through |
| s/s of Rheumatoid arthritis : gradual onset | vague/not apparent; inflammation, fever, weakness, anorexia, aching and stiffness in A.M. |
| s/s of Rheumatoid arthritis : disease progression | painful, tender, stiff, decreased ROM, redness, edema, spongy with palpation |
| s/s of Rheumatoid arthritis : late stages | joint deformities and decreased functional use; ulnar deviation, swan neck, boutonniere deformity |
| Patient may develop what during late stages of Rheumatoid arthritis? | Vasculitis, pericarditis, splenomegaly |
| How to diagnose Rheumatoid arthritis | presence of antibodies ACPA or RF |
Created by:
Anna91715
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