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Concept Dis. Ch.14

Hematopoietic & Lymphatic Systems

the average human has __ of blood 5 quarts
iron, B12, folic acid, & protein are all raw materials required for blood synthesis within the marrow
erythropoiesis is regulated by erythropoietin
etiologic classification of anemia might be blood-loss related
anemia caused by folic acid deficiency can be secondary to a poor diet
anemia caused by bone marrow damage is initially managed with blood transfusion
can be acquired through mechanical trauma secondary to an enlarged spleen or by insertion of an artificial heart valve hemolytic anemia
hemochromatosis can eventually lead to organ damage
patient's medical history & physical exam, complete blood count, reticulocyte count, & bone marrow study are used to evaluate & diagnosis anemia
is a complication of polycythemia increased blood viscosity
nodes of the lymph system serve as filters
enlarged, tender, and inflamed lymph nodes secondary to the spread of an infection into the lymphatic channels lymphadenitis
localized infection, systemic infection, lymphoma, & metastatic tumor can all be indicated by swollen lymph nodes
Individuals who have had a ___ develop problems with the immune system splenectomy
decrease in hemoglobin or red cells or both anemia
lymphocyte that differentiates into plasma cells and is associated with humoral immunity B lymphocyte
cell that contains numerous variable-sized granules that stain intensely purple with basic dyes. See also eosinophil basophil
cell whose cytoplasm is filled with large, uniform granules that stain intensely red with acid dyes eosinophil
virus that causes infectious mononucleosis Epstein-Barr virus
precursor cell in the bone marrow that gives rise to red blood cells erythroblast
humoral substance made by the kidneys that regulates hematopoiesis erythropoietin
type of hemoglobin containing two alpha and two gamma chains, which is able to take up and release oxygen at much lower PO2 than in adult hemoglobin fetal hemoglobin
oxygen partial pressures PO2
genetic disease characterized by excessive iron absorption, leading to accumulation of excessive amounts of iron in the body, causing organ damage hemochromatosis
oxygen transport protein within red cells composed of an iron-porphyrin complex combined with a protein chain hemoglobin
anticoagulant obtained from the liver heparin
Hodgkin disease is one type of lymphoma
abnormally small number of leukocytes in the peripheral blood leukopenia
mononuclear blood cell produced in lymphoid tissue that takes part in cell-mediated and humoral immunity lymphocyte
lymphoma is a neoplasm of lymphoid cells
abnormal red cell precursor resulting from vitamin B12 or folic acid deficiency megaloblast
leukocyte having a kidney-shaped nucleus and light blue cytoplasm; a phagocytic cell that forms part of the reticuloendothelial system monocyte
leukocyte having a multilobed nucleus whose cytoplasm is filled with fine granules neutrophil
macrocytic anemia caused by inability to absorb vitamin B12 as a result of inadequate secretion of intrinsic factor by gastric mucosa pernicious anemia
small pinpoint hemorrhage caused by decreased platelets, abnormal platelet function, or capillary defect petechia
component of the blood; a roughly circular or oval disk concerned with blood coagulation platelet
increased number of red cells polycythemia
may be caused by some types of chronic heart or lung disease secondary polycythemia
may be due to marrow erythroid hyperplasia of unknown causes primary polycythemia
young red cell that can be identified by special staining procedures reticulocyte
type of lymphocyte associated with cellmediated immunity T lymphocyte
deficiency of platelets thrombocytopenia
Created by: lfrancois