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Microbiology Exam 3
Question | Answer |
---|---|
1. What does the term infection refer to? | |
2. When does the human body usually begin to be colonized by normal biota? | |
3. Where can resident biota be found in/on the human? | |
4. What is microbial antagonism? | |
5. What are the normal biota of the skin? | |
6. What are opportunistic pathogens? | |
7. What factors weaken host defenses against infections? | |
8. How does the greatest number of pathogens enter the body? | |
9. What are the microbial methods of adhesion? | |
10. What is phagocytosis? What types of blood cell performs this? | |
11. What are the virulence factors microbes can possess? I.e. capsules, endo/exotoxins..etc. | |
12. Know the characteristics of endotoxins and exotoxins. | |
13. What are enterotoxins? | |
14. What is the function of fimbriae, capsules, coagulase, leukocidins, and hemolysins? | |
15. Know all the stages of disease and basics about what is going on. I.e. prodromal, incubation..etc. | |
16. Know these definitions: secondary infection, mixed infection , acute infection , local infection , and toxemia. | |
17. Know what a sign, symptom, and syndrome are. | |
18. What is leukopenia? | |
19. Know the terms bacteremia, septicemia, and viremia. | |
20. What are the normal portals of exit for an infectious disease? | |
21. What is a carrier? What is a vector( both mechanical and biological kinds)? Reservoir? What can be a reservoir? | |
22. What are the universal precautions for handling patients and body substances? | |
23. When would you use Koch’s postulates? | |
24. What is epidemiology? | |
25. Know the terms epidemic, endemic, pandemic, and sporadic. | |
26. What is involved in the 1st line of defense? | |
27. What body area depends on cilia to help clear the area of microbes? | |
28. What are the physical barriers to pathogens? | |
29. How do immune system cells differentiate between self and foreign cells? | |
30. What is an antigen? Antibody? | |
31. Which WBC releases histamine and is the least numerous? | |
32. Which WBC is 20-30% of WBCs and is part of the 3rd line of defense? | |
33. Which WBC is most numerous and has a multi-lobed nucleus? | |
34. What do plasma cells do? | |
35. Which lymphocyte functions in humoral immunity? What about cellular? | |
36. What are the four signs and symptoms of inflammation? | |
37. What are the benefits of a fever? | |
38. Know all the characteristics of interferon AND complement. | |
39. What specific WBCs are involved in acquired specific immunity? | |
40. What do Th cells do? | |
41. Lymphocyte maturation includes what steps and locations for T and B cells? | |
42. The major histocompatability complex is | |
43. Class II MHC genes code for a. certain secreted complement components. b. self receptors recognized by T lymphocytes. c. all HLA antigens. d. receptors located primarily on macrophages and B cells (APCs). | |
44. Class I MHC genes code for | |
45. The region of each antibody molecule where amino acid composition is highly varied from one clone of B lymphocytes to another and where the antigen is bound is the? | |
46. What is an epitope? | |
47. What is a hapten? | |
48. Which of the following is not a property of B cells? | |
49. What are APCs, what cells can be one? How do they work? | |
50. Know all characteristics of the Fc region of an immunoglobulin/antibody. | |
51. What is neutralization? Opsonization? | |
52. Which process involves a more rapid synthesis and greatly increased titer of antibody when the immune system is subsequently exposed to the same antigen? | |
53. Know ALL characteristics of the 5 classes of immunoglobulins/antibodies. I.e. is it a monomer, dimer, or pentamer. Smallest, largest. Which can cross placenta..etc. | |
54. What type of cells/tissues do Tc target? | |
55. What allows adaptive/specific immunity to provide long-lasting protection? | |
56. Be able to classify situations as artificial/natural and active/passive immunity. | |
57. What did Jenner’s work involve? | |
58. How are killed or inactivated vaccines prepared? | |
59. What do acellular and subunit vaccines contain? | |
60. What activates the classical pathway of complement? | |
61. Which hypersensitivity categories involve immunoglobulin? Which one involves T cells? | |
62. Classify these as Type I, II, III, or IV: | |
63. What is the definition of hypersensitivity? | |
64. What is systemic anaphylaxis? What does it include? | |
65. What is desensitization? | |
66. Know all about hemolytic disease of the newborn and what each person must have for the Rh factor.etc. | |
67. Know the terms isograft, autograft, allograft, and xenograft. | |
68. What is autoimmunity typically caused by? | |
69. What are the phenotypic methods of identification? | |
70. What types of tests are Biochemical tests? | |
71. What can be used for specimen collections? | |
72. What specimens require a sterile needle collection? | |
73. What is serology? | |
74. What is specificity? Sensitivity? | |
75. What is a titer? | |
76. What techniques might be used to analyze tiny/minute DNA samples? |