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Chap 13 MedTerm
The Blood System
Question | Answer |
---|---|
Hematopoietic Stem Cell | cell in the bone marrow that gives rise to all types of blood cells |
Reticulocyte | an immature red blood cell |
Erythrocytes | red blood cell |
Characteristics of RBC's- Erythrocytes | Anuclear, Biconave, Red pigment heme, carry oxgyen, filled with hemoglobin, flexible, travel sing file through the capillaries |
erythropoietin mechanism | |
How many RBC's in a cubic millimeter of blood? | 5 million |
How long does a RBC live? | 120 days |
How many hemoglobin molecules are in a single RBC? | 250,000,000 |
Sider/o? | iron |
How many RBC destroyed per second? | 2.4X10^6 |
Bilirubin | Orange yellow pigment formed from destruction of hemoglobin |
What happens to all that hemoglobin? | Excreted by liver in bile, reused or stored in live spleen, or bone marrow |
Neutrophil | leukocyte formed in bone marrow and having neutral staining granules |
eosinophil | leukocyte with dense, reddish granules; associated with allergic reactions |
neutrophil | white blood cell that destroys foreign material by phagocytosis, fighting bacterial infection |
lymphocyte | leukocyte formed in lymph tissue; produces antibodies |
leukocytes | neutrophil, eosinophil, monocyte, large lymphocyte |
phagocyte | eats bacteria |
eosinophil | fights against allergies and patastic infections, phagocyte |
monocyte | become marcophages, large phagocytes, eats tissue debris |
platelets | clotting mechanism |
plasma | liquid portion of blood |
lymphocyte | controls the immune response; makes antibodies to antigens (immunoglobulins) |
four major proteins | albumin, globulins, fibrinogen and prothrombin (the last two are clotting proteins) |
albumin | plasma protein that maintains the proper amount of water in blood (blood protein) |
globulins | protein in plasma; can be separated into alpha, beta, and gamma types |
fibrinogen & prothrombin | clotting process |
Blood types: | TYPE A, TYPE B, TYPE AB, and TYPE O |
which type is the universal donor? | Blood type O, important of maintaining the blood, most common blood type ANTI A and ANTI B |
hemolytic disease of the newborn? | 1. mother and baby's blood mixes during birth, 2. antibodies against Rh+ blood are formed by the mother, 3. mother's antibodies destroys (lyse) the second baby's blood |
fibrin clot | |
Abnormalities of RBC: anisocytosis | cells are unequal in size |
Abnormalities of RBC: hypochromia | cells have reduced color (less hemoglobulin) |
Abnormalities of RBC: macrocytosis | cells are large |
Abnormalities of RBC: microcytosis | cells are small |
Abnormalities of RBC: poikilocytosis | cells are irregularly shaped |
Abnormalities of RBC: spherocytosis | cells are spherical (loss of normal concave shape) |
anemia | deficiency in erythrocytes or hemoglobin |
aplastic anemia | failure of blood cell production in the bone marrow |
sickle cell | hereditary disorder of abnormal hemoglobin producing sickle shaped erythrocytes and hemolysis |
thalassemia | inherited disorder of abnormal hemoglobin production leading to hypochromia |
pernicious anemia | lack of mature erythrocytes caused by inability to absorb vitamin B12 into the bloodstream |
hemolytic anemia | reduction of red cells |
siderpenia anemia | |
polycythemia VERA PV | increased red blood cells |
Cause of sickling | low O2 |
Hemophilia | excessive bleeding caused by hereditary lack of VIII and IX necessary for blood clotting |
purpura | multiple pinpoint hemorrhages; blood accumulates under the skin |
thrombocytopenia | deficiency of clotting cells |
acute leukemia | |
leukemia | ACUTE: Sudden onset of immature leukocytes - most often seen in children CHRONIC: Progresses slowly over time - mature lymphocytes most often seen in adults |
mononucleosis | caused by EBV Epstein Barr virus - carried and transmitted by saliva, infectious disease marked by increased numbers of mononuclear leukocytes and enlarged cervical lymph nodes |