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Path: Skin tumors
basic as can be
| Question | Answer |
|---|---|
| Seborrheic Keratosis | Benign: papillomatous or plaque like proliferation of ordrly mature epidermal cells with both basaloid and squamous feartures |
| Skin Tag | Core of reticular dermal collagen covered by normal or papillomatous seborrheic keratosis like epidermis |
| Epidermal cysts (wen or sebaceous) | Cystic dilation of the follicular infundibulum lined with epidermis adn filled with keratin |
| Keratoacanthoma | florid downgrowth of well differentiated squamous epithelium to form symmetric cup shaped tumor |
| Adnexal Tumor | Tumor of sweat, sebaceous and follicular origin |
| syringoma | adnexal tumor of the eccrine sweat gland under the eye |
| trichoepithelioma | Adnexal tumor with follicular differentiation |
| Actinic Keratosis | epidermal proliferation with some cytologic atypia of keratinocytes (near basilar layer) may have cutaneous horns and solar elastosis fibers from sun damage |
| Bowen's disease | full thickness epidermal atypia with marked dypslasia of epidermal cells |
| SCC | proliferation of atypical eosinophilic sqamoid epithelium wiht varying degrees of keatin production and derma INVASION |
| Basal cell carcinoma | nodular prolifeation of atypical basal cells with peripheral palisading and retraction from adjacent epidermis |
| Sclerosing BCC | small tumor islands embedded in fibrotic stroma |
| Superficial BCC | nests of basal cells attached to the epidermis |
| Dermatofibroma | localized intradermal prolifeationa of fibroblasts and histiocytes |
| Infantile cap. hemangioma | sheets of closely packed capillaries that form large nodules with pushing margins |
| Lobular capillary hemangioma | pyogenic hemangioma lobular arrangement of capillaries that can be obscured by surface ulceration, edema, and inflammation |
| Kaposi's Sarcoma | Proliferation of uniform spindle cells that form patches or nodules in superficial dermis with erythrocytes in narrow slits between spindle cells |
| Lymphoid Infiltate | mixed cell population of small and large lymphocytes |
| when is lymphoid infiltrate benign | when there are germinal centers eosinophils and plasma/giant cells |
| what are leukemia lymphiod infiltrate findings | monomorphic cytologically atypical dermal and cutaneous infiltrates tiwht diffuse destructive patterns |
| Mycoiss fungoids | diagnostic band like infiltrates in the superficial dermis composed of atypical lymphid cells with hyperchromatic nuclei showing folded nuclear contours |
| Pautrier microabscess | cells expand (Mycosis fungoids) into the epidermis adn form intraepidermal abscesses |
| seborrheic keratoiss | tan brown stuck on |
| Skin tag | small flesh colored pailloma |
| Epidermal cysts (wen or sebaceous cysts | Cystic dilation of follicular infundibulum lined iwht epithelium filled with keratin |
| Keratoacanthoma | elevated dome like with keratin crater |
| Adnexal Tumor | tumor of the sweat sebacceous or follicular gland |
| syringoma | adnexal tumor of the sweat gland under the eye |
| Tricchoepithelioma | follicular differentiation |
| Actinic keratosis | premalignant papules on sunesposed areas with most SCC arising from them |
| Bowen's Disease | SCC in situ prestens as a plaque anywhere not just sun exposed full thickness epidermal atypia once invasive 40% mets |
| Bowens diseases is associated with | HPV and arsenic exposure |
| SCC | from actinic keratosis rarely mets can arise de novo from mucocutaneous jn, burns or radiation car, chronic usler or drainins sinus 10-40 percent mets |
| Basal Cell Carcinoma | most common malignant skin tumor in sunexposed pearly trnaslucent papule or nodule "rodent ulcer" |
| Sclerosing BCC | tumor island in fibrotic stroma |
| superficial BCC | scaly patch iwht a nest of basal cell attached to epidermis |
| Dermatofibroma | firm immobile intradermal nodule on extremities of young and middle ages with intradermal proliferation of fibroblasts and histiocytes |
| Capillary hemangioma | external nose and nasal vestibules |
| infantile hemangioma | strawberry hemangioma |
| Lobular capillary hemangioma | pyogenic granuloma |
| Kaposi's sarcoma | aids adn elderly in africa it affects younger with Herpes 8 but those with kaposi tend to have a better prognoiss |
| Lymphoid infiltrate | often benign from arthropod bites, infectious agents, foreign material, when the immune cells are normal it is benign when they are abnomal it is malignant |
| Mycosis fungoids | T cell lymphoma mostly primary cutaneous with lymphomas will disemminate |
| Pautrier microabscesses | when the cells extend into the epidermis to form absecss long term remission are hard to come by even in the first stage this is a mycosis fungoides |
Created by:
jmuame03
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