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Blood RD

hemophilia A hereditary disorder in which there is an impairment of the blood clotting mechanism
hemoglobin A specialized plasma protein containing iron which gives blood its red colour and also carries oxygen to body tissues
immunocompetent Ability to develop an immune response or recognize antigens and respond to them
edema Abnormal accumulation of fluids in the intercellular spaces of the body
disseminated intravascular coagulation (DIC) Abnormal activation of the proteins involved in blood coagulation, causing small blood clots to form in vessels and cutting off the supply of oxygen to distal tissues
thrombocytopenia Abnormal decrease in platelets caused by low production of platelets in the bone marrow or increased destruction of platelets in the blood vessels, spleen, or liver
hemosiderosis Abnormal increase of iron in the blood
leukocytosis Abnormal increase of white cells
lymphadenopathy Any disease of the lymph nodes
hemoglobinopathy Any disorder caused by abnormalities in the hemoglobin molecule
immunotherapy Any form of treatment that alters, enhances, stimulates, or restores the body's natural immune mechanisms to treat disease
von Willebrand disease Bleeding disorder caused by a deficiency of von Willebrand factor, a "sticky" protein that lines blood vessels and reacts with platelets to form a plug that leads to clot formation
antiserum Blood serum that contains antibodies
megakaryocyte Cell with a large nucleus; fragments become platelets
cytokine Chemical substance produced by certain cells that initiates, inhibits, increases, or decreases activity in other cells
pernicious anemia Chronic, progressive anemia found mostly in people older than age 50 due to lack of sufficient vitamin B12 needed for blood cell development
blood Composed of a liquid portion called plasma, and a solid portion containing RBCs, WBCs, and platelets
graft-versus-host-disease (GVHD) Complication that occurs following a stem cell or bone marrow transplant in which the transplant produces antibodies against recipient's organs that can be severe enough to cause death
phagocytosis Condition of ingesting cells
leukopenia Decrease in white blood cells
thrombocytopenia Decrease of platelets
erythropenia Decreased red blood cells
antimicrobials Destroy bacteria, fungi, and protozoa, depending on the particular drug, generally interfering with the functions of their cell membrane or their reproductive cycle
thrombolysis Destruction of a clot
hemolytic anemia Destruction of RBCs, commonly resulting in jaundice
dyspnea Difficulty breathing
adenopathy Disease of a gland
thrombolytics Dissolve blood clots by destroying their fibrin strands
vertigo Dizziness
myeloblast Embryonic WBC formed in bone marrow
splenomegaly Enlargement of the spleen
autoimmune disease Failure of the body to accurately distinguish between what is "self" and what is "non-self"
hematopoiesis Formation of blood cells and platelets in the bone marrow
bone marrow MRI Highly sensitive imaging procedure that detects lesions, and changes in bone tissue and bone marrow, especially in multiple myeloma
allergy injections Injection with increasing strengths of the offending antigen given over a period of months or years to increase tolerance to an antigen responsible for severe allergies
reticulocyte Immature RBC
folic-acid deficiency anemia Inability to produce sufficient red blood cells due to the lack of folic acid, a B vitamin essential for erythropoiesis
transfusion Infusion of blood or blood products from one person to another
homologous BM transplant Infusion of bone marrow or stem cells from a compatible donor after a course of chemotherapy and/or radiation; also called allogenic transplant
bone marrow transplant Infusion of healthy bone marrow stem cells after the diseased bone marrow is destroyed by chemotherapy and/or radiation therapy; used to treat leukemia, aplastic anemia, and certain cancers
autologous BM transplant Infusion of the patient's own bone marrow or stem cells after a course of chemotherapy and/or radiation therapy
sickle cell anemia Inherited anemia that causes RBCs to become crescent-or sickle shaped when oxygen levels are low
lymphoscintigraphy Introduction of a radioactive tracer into the lymph channels to determine lymph flow, identify obstructions, and locate the sentinel node
iron-deficiency anemia Lack of sufficient iron in RBCs
monocyte Leukocyte that is phagocytic; has a large nucleus
eosinophil Leukocyte that protects the body by releasing toxins to destroy harmful invaders
basophil Leukocyte that releases histamines and heparin; slightly phagocytic
hematoma Localized accumulation of blood, usually clotted, in an organ, space, or tissue due to a break in or severing of a blood vessel
hypotension Low blood pressure
multiple myeloma Malignant tumour of plasma cells in bone marrow
erythrocyte Mature red blood cell
antifibrinolytics Neutralize fibrinolytic chemicals in the mucous membranes of the mouth, nose, and urinary tract to prevent the breakdown of blood clots
monospot test Nonspecific rapid serological test for the presence of the heterophile antibody, which develops several days after infection by Epstein-Barr virus, the organism that caused infectious mononucleosis
phlebotomy Obtaining blood for the purpose of testing
immunologist One who specializes in the study of protection
thrombocythemia Overproduction of platelets, leading to thrombosis or bleeding disorders due to platelet malformations
hypochromic Pertaining to decrease of colour
thrombocyte Platelet; initiates blood clotting
sepsis Presence of bacteria or their toxins in the blood; also called septicemia or blood poisoning
fat-soluble vitamins Prevent and treat bleeding disorders resulting from a lack of prothrombin, which is commonly caused by vitamin K deficiency
anticoagulants Prevent blood clot formation by inhibiting the synthesis or inactivating one or more clotting factors
antivirals Prevent replication of viruses within host cells
graft rejection Process in which a recipient's immune system attacks a transplanted organ or tissue
antibody (Ab) Protective protein produced by B lymphocytes in response to the presence of a foreign substance called an antigen
tachycardia Rapid heart beat
erythema Redness of the skin
anemia Reduction in the number of circulating red blood cells
bone marrow aspiration Removal of a small sample of bone marrow using a thin aspirating needle for microscopic examination
lymphadenectomy Removal of the lymph nodes, especially in surgical procedures undertaken to remove malignant tissue
sentinel node excision Removal of the first lymph node that receives drainage from cancer-containing areas and the one most likely to contain malignant cells
thymectomy Removal/excision of the thymus gland
myeloid Resembling bone marrow
complete blood count (CBC) Series of tests that includes hemoglobin; hematocrit; red and white blood cells counts; platelet counts; and differential count; also called hemogram
aplastic anemia Serious form of anemia associated with bone marrow failure and resulting in erythropenia, leukopenia, and thrombocytopenia
Natural Killer (NK) cells Specialized lymphocytes that kill abnormal cells by releasing chemicals that destroy the cell membrane, causing its intercellular fluids to leak out
hemocytoblast Stem cell, from which other blood cells develop
antigen Substance, recognized as harmful to the host, that stimulates formation of antibodies in an immunocompetent individual
bile pigment Substances derived from the breakdown of hemoglobin and excreted by the liver
lymphedema Swelling, primarily in a single arm or leg, due to an accumulation of lymph within tissues caused by obstruction or disease in the lymph vessels
partial thromboplastin time (PTT) Test that measures the length of time it takes blood to clot to screen for deficiencies of some clotting factors; also called activated partial thromboplastin time
prothrombin time (PT) Test that measures the time it takes for prothrombin to form a clot; also called pro time
blood culture Test to determine the presence of pathogens in the bloodstream
shilling test Test used to diagnose pernicious anemia by determining if the body properly absorbs vitamin B12 through the digestive tract
antinuclear antibody (ANA) Test to identify antibodies that attacks the nucleus of the individual's own body cells
plasma The liquid portion of blood where blood cells are suspended
neutrophil The most numerous white cell, highly phagocytic
morphology The study of shape
viscous Thick, sticky
myeloid tissue Tissue which resembles the myelocyte of bone marrow
lymphoma Tumour of lymph tissue
granulocyte Type of white blood cell containing granules; formed in the red bone marrow
aranulocyte Type of white blood cell without granules
biological Use of immune stimulators to enhance the immune response in the treatment of certain forms of cancer, rheumatoid arthritis, and Chron disease; also called biologic therapy or biotherapy
lymphangiography Visualization of lymphatic channels and lymph nodes using a contrast medium to determine blockages or other pathologies of the lymph system
systemic lupus erythematosus (SLE) Widespread autoimmune disease that may affect the skin, brain, kidneys, and joints and causes chronic inflammation; also called discoid lupus if symptoms are limited to the skin
lymphocytes White blood cell in blood and lymphatic tissues; provides protection from bacteria
leukocyte White blood cell; prevents invasion of foreign micro-organisms
Created by: Jessica Longboat
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