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Bone remodeling
| Question | Answer |
|---|---|
| Bone remodeling fact | -occurs throughout life -allows older mineral deposits to be released from home into bloodstream |
| What happens if removal of bone is faster than replacement? | Bones weaken |
| What does bone remodeling involve (workers) | -osteocytes, osteoblasts & osteoclasts |
| If bone rebuilding predominates (example: working out) what happens? | Bones strengthen |
| Is bone turnover rate high or low? | High |
| What are the effects of exercise on bone? | -they adapt to stress -they become thicker and stronger -it stimulates osteoblasts (bone builders) |
| Bone degeneration | -bone degenerates quickly -up to 1/3 of bone Mass can be lost in a few weeks of inactivity |
| What minerals are required for bone health? | -calcium -phosphorus -magnesium -fluoride -iron -manganese |
| Vitamin C affect on bone | Is required for collagen synthesis and stimulates osteoblast differentiation |
| Vitamin A affect on bone | Stimulates osteoblast activity |
| Vitamins K & B12 | Required for synthesis of bone proteins |
| What maintains calcium in homeostasis | -parathyroid hormone -calcitonin |
| What hormones stimulate bone growth? | -growth hormone -thyroxine |
| What are hormones stimulate bone growth | -estrogen -testosterone |
| What is calcitriol? | -made in kidneys -essential for normal calcium and phosphate in absorbtion in digestive tract |
| How much calcium do your bones store? | 90% in addition to other minerals |
| What is the most abundant mineral in the body? | Calcium |
| What physiological processes is calcium vital to | -muscle contractions -nerve impulse transmission |
| How is homeostasis maintained in bone | -two negative feedback loops |
| What is Parathyroid hormone (PTH) | -produced by Parathyroid glands which detect low calcium levels |
| How do Parathyroid glands increase blood calcium levels? | -stimulating osteoclasts activity -inhibits osteoblast activity -increasing interesting absorbtion of calcium by enhancing calcitriol secretion by kidneys -decreasing calcium excretion by kidneys |
| What is calcitonin | Thyroid gland detects high blood calcium levels -is secreted by C cells in there gland -important in children and pregnant/lactating women |
Created by:
Garciamentzer
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