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Bone formation and g
| Question | Answer |
|---|---|
| Ossification (osteogenesis) | Process of bone formation -begins in embryo and continues thru childhood |
| Calcification | Deposit of clacium salt (occurs during bone formation) |
| What are the two forms of ossification? | Endochondral-hyaline cartilage model Intramembranous ossofication- mesenchymal model |
| What age do bones stop growing? | 25 |
| Endochondral ossification | -how most bones form -developed inside hyaine cartilage |
| Primary ossofication center | -cartilage is surrounded by perichodrium with immature chondeoblasts -cartilage is gradually replaced by bone |
| Epiphyseal closure | Puberty affecting cartilage growth and upping osteblast |
| Articular cartilage | this cartilage prevents damaging the joint from home to bone contact |
| Interstitial growth | Growth in length |
| Epiphyseal closure | Completion of bone growth |
| Zone of reserve cartilage | Cells are not directly involved in bone growth |
| Zone of proliferation | Actively dividing chondeoblasts, push cells into next zone (elongate bone) |
| Zone of hypertrophy and maturation | Mature chondrocytes in lacuna, actively producing ECM |
| Zone of calcification | Chondrocytes for as ECM calcified and nutrients are cut off |
| Zone of ossification | Osteoblasts and osteoclasts present, replace calcified tissue with new osteoid matrix |
| Appositional growth | Growth in width/circumstance -thicken/strengthens -deepest layers become replaces by osteons -during process, osteoclasts slowly remodel and remove bone matrix at inner surface of bone |
| Intramembranous ossification (dermal ossification) | -occurs in dermis -produces dermal bones like cranial, lower jaw, collar bones |
| How are areas of spongy bone remodeled? | Using diploƫ and thin covering of compact bone |
| Hope does blood supply get to bones? | -internal artery and veins -pass through nutrient foramina in diaphysis |
| What supplies blood to epiphyseal cartilages where bone growth occurs? | Metaphyseal vessels |
| What supplies blood to superficial osteons and secondary ossification centers? | Peiosteal vessels |