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Hematology & Coag.
Hematology & Coagulation Studies
| Term | Definition |
|---|---|
| ESR | increased in an inflammatory disease like rheumatoid arthritis |
| eosinophil | WBCs would be elevated during an allergic reaction |
| oxygen-carrying capacity | determines the hemoglobin content of the RBCs |
| hematocrit | volume of packed RBCs |
| 120 days | the RBC remains functional in the blood stream without a nucleus |
| RBCs | most plentiful cellular component found in the blood |
| how many different WBCs are there? | 5 |
| thrombocyte | main function hemostasis and providing a surface for clotting proteins |
| general causes of anemia | blood loss, insufficient production of RBCs and excessive destruction of RBCs |
| CBC consists of | WBC count, RBC count, Platelet estimate, WBC differential, hemoglobin, hematocrit and RBC indices |
| middle layer of a centrifuged blood sample, separtaed into 3 layers | WBC and platelets |
| INR | ratio that compares results to ensure consistency from one lab to another |
| lymphocyte | second most plentiful WBC in a differential count |
| RBC indices | indicators of anemia |
| patient with COPD and CHF may be more likely to have | increased hemoglobin |
| sickle cell anemia | inherited disorder caused by the presence of hemoglobin S |
| patient with elevated PT or INR are in danger of | internal bleeding |
| pancytopenia | decrease in all blood cell types |
| leukopenia | low number of total WBCs also referred to as leukocytopenia |
| pernicious anemia | decreased number of RBCs caused by a lack of vitamin B12 |
| sickle cell anemia | inherited disorder which causes a sickle-shaped RBC, interfering with the ability of the cell to carry oxygen |
| leukocytosis | increase in. the total number of WBCs |
| thrombocytosis | an overproduction of platelets |
| hemolytic anemia | inherited or acquired disorder that results in the destruction of the RBCs |
| aplastic anemia | anemia caused by bone marrow disorders that inhibit or decrease the productions of RBCs |
| erythrocytosis | abnormal increase in the number of RBCs |
| leukemia | malignant cancer of WBCs in which the bone marrow creates abnormal and dysfunctional WBCs |
| monocyte | large, irregularly shaped nucleus |
| lymphocyte | small count of cytoplasm surrounding a round to oval-shaped nuleus |
| basophil | coarse purplish-black cytoplasmic granules |
| neutrophil | pinkish-purple fine granules in the cytoplasm |
| eosinophil | coarse organe-red granules in the cytoplasm |
| PT | 10-13 seconds |
| aPTT | 25-40 seconds |
| INR | 0.8-1.1 |