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Hormone Replacement
Unmanned
Question | Answer |
---|---|
In which group of women is HRT most commonly used? | Postmen women |
Give the routes of admin of HRT other than oral | Transdermal patch, subcutaneous, intramuscular |
Forms in which HRT is available | Oral (pill), Intravaginal cream, Intramuscular depot, subcutaneous depot implant, transdermal patch |
State uses of HRT | Local relief to urogenital tract ex atrophic vaginitis Relief of hot flushes |
Give an advantage of each type of HRT prep | Oral: non-invasive, widely available, affordable Cream: Local relief of UG tract IM & subderm prep: decreased freq of admin Transderm: non-invasive, decreased freq of admin, lower dose, red risk of gallbladder disease, easy removal |
What are the risks of hRT? | 1. Breast ca 2. Endometrial Ca 3. Stroke 4. Coronary artery disease |
how may the risks of hRT be mitigated | Risk due to unopposed oestrogen so progestin component may be added for 12-14 dys or using a combined oestrogen/progestin prep |
Absolute C/I to HRT | 1. Unexplained vag bleeding 2. Liver disease 3. Breast ca 4. endometrial Ca |
Relative C/I to hRT | 1. HTN 2. Fibroids 3. Gallbladder disease 4. Migraines 5. Thrombophlebitis |
List changes that may occur in menopause | 1. Hot flushes 2. GU: atrophic vaginitis 3. CVS risk increases (atherosclerosis) 4. Altered Ca met- osteoporosis 5. Psych: anxiety & depression 6. Skin: wrinkling, increased dependence |