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Hormone Replacement


In which group of women is HRT most commonly used? Postmen women
Give the routes of admin of HRT other than oral Transdermal patch, subcutaneous, intramuscular
Forms in which HRT is available Oral (pill), Intravaginal cream, Intramuscular depot, subcutaneous depot implant, transdermal patch
State uses of HRT Local relief to urogenital tract ex atrophic vaginitis Relief of hot flushes
Give an advantage of each type of HRT prep Oral: non-invasive, widely available, affordable Cream: Local relief of UG tract IM & subderm prep: decreased freq of admin Transderm: non-invasive, decreased freq of admin, lower dose, red risk of gallbladder disease, easy removal
What are the risks of hRT? 1. Breast ca 2. Endometrial Ca 3. Stroke 4. Coronary artery disease
how may the risks of hRT be mitigated Risk due to unopposed oestrogen so progestin component may be added for 12-14 dys or using a combined oestrogen/progestin prep
Absolute C/I to HRT 1. Unexplained vag bleeding 2. Liver disease 3. Breast ca 4. endometrial Ca
Relative C/I to hRT 1. HTN 2. Fibroids 3. Gallbladder disease 4. Migraines 5. Thrombophlebitis
List changes that may occur in menopause 1. Hot flushes 2. GU: atrophic vaginitis 3. CVS risk increases (atherosclerosis) 4. Altered Ca met- osteoporosis 5. Psych: anxiety & depression 6. Skin: wrinkling, increased dependence
Created by: IonaDel
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