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Diuretics. Trade name: lasix

Indication Edema Hypertension Acute pulmonary edema/ Hypertensive crisis/ increase intracranial pressure Hyperkalemia Hypermagnesemia
Route By mouth or injection
Contraindication Anuria Hypersensitivity to furosemide or sulfonamides
Side effects Hyperuricemia ( excessive uric acid in the blood), hypokalemia (really low potassium level) Muscle cramps, itching or rash, weakness, vertigo, diarrhea, stomach pain, constipation, dehydration, nausea, vomiting, anaphylaxis
Mechanism of action Loop diuretic; inhibits reabsorption of sodium and chloride ions at proximal and distal renal tubules and loop of Henle; by interfering with chloride-binding cotransport system, causes increases in water, calcium, magnesium, sodium, and chloride
Absorption Peak effect" < 15min (iv), 1-2 hour (PO)
Dose 20-40mg: Edema (IV/IM), Hypermagnesemia (IV, PRN) 20-80mg: hypertension (PO), Edema (PO/once) 40-80mg: hyperkalemia
Created by: bttr