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Furosemide
Diuretics. Trade name: lasix
Question | Answer |
---|---|
Indication | Edema Hypertension Acute pulmonary edema/ Hypertensive crisis/ increase intracranial pressure Hyperkalemia Hypermagnesemia |
Route | By mouth or injection |
Contraindication | Anuria Hypersensitivity to furosemide or sulfonamides |
Side effects | Hyperuricemia ( excessive uric acid in the blood), hypokalemia (really low potassium level) Muscle cramps, itching or rash, weakness, vertigo, diarrhea, stomach pain, constipation, dehydration, nausea, vomiting, anaphylaxis |
Mechanism of action | Loop diuretic; inhibits reabsorption of sodium and chloride ions at proximal and distal renal tubules and loop of Henle; by interfering with chloride-binding cotransport system, causes increases in water, calcium, magnesium, sodium, and chloride |
Absorption | Peak effect" < 15min (iv), 1-2 hour (PO) |
Dose | 20-40mg: Edema (IV/IM), Hypermagnesemia (IV, PRN) 20-80mg: hypertension (PO), Edema (PO/once) 40-80mg: hyperkalemia |