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WBC
White blood test
Term | Definition |
---|---|
Categories of Leukocytes | Granular and nongranular |
Granular leukocytes | Neutrophils, Eosinopihls, and Basophils |
Nongranular leukocytes | Lymphocytes and Monocytes |
Range of Neutrophils | 40%-75% |
Range of Eosinophils | 1%-6% |
Range of Basophils | 0%-2% |
Range of Lymphocytes | 20%-40% |
Range of Monocytes | 3%-10% |
Diapedesis | Movement of the WBC through the capillaries |
Phagocytosis | The engulfing and destruction of pathogens and damaged cells |
Pus contents | dead leukocytes, dead bacteria, and dead tissue cells |
Normal value for WBC | 4,500 to 11,000/ mm cubed |
Suppuration | infected area |
location of WBC | mostly resides in connective tissue and throughout the body |
Granular | contains distinct granules in cytoplasm |
Non-granular | contain few or no granules in cytoplams |
Leukocytosis | Increase in leukocytes |
Cause of Leukocytosis | pathological and physiological conditions |
Pathological conditions are associated w/ | infectious mononucleosis, pneumonia, chicken pox, appendicitis, tonsillitis, hemorrhaging, and Leukemia |
Physiological conditions are associated w/ | emotional stress, exposure to cold conditions, menstruation, Pregnancy and labor, strenuous exercise |
Leukopenia | decrease in leukocytes |
Conditions associated w/ Leukopenia | Cirrhosis, infectious hepatitis, bone marrow depression, chemotherapy, radiation therapy, viral infection |
Neutrophils | Most common and most numerous WBC |
First responders | Neutrophils |
2 types of Neutrophils | segmented and non-segmented |
bands or stabs | non-segmented parts |
Life span of the neutrophil | few days |
Production of neutrophils | takes place in the bone marrow |
Amoebic movement | a crawling like movement in which the cell forms temporary projections called pseudopodia to be able to move |
Pseudopodia | False feet |
Neutrophilla | increase in neutrophils |
Neutrophilla is associated w/ | acute bacterial infection infections, parasitic infections, liver disease |
Neutropenia | Decrease in neutrophils |
Neutropenia is associated w/ | Acute viral infection, blood diseases, hormone disease, and chemotherapy |
Location of Neutrophils | moves through veins into tissue |
Lymphocytes | Smallest and 2nd most common white blood cells |
Life span of lymphocytes | 2 weeks to several years |
3 types of of lymphocytes | B cells, T cells, and natural killer cells |
Lymphocytosis | Increase in lymphocytes |
Conditions associated with lymphocytosis | Addison's disease, acute and chronic infections, lymphocytic leukemia, carcinoma, and hypothyriodism |
Lymphopenia | decrease in lymphocytes |
Conditions associated with lymphopenia | Aids or HIV infections, cardiac failure, cushing's disease, hodgkin's disease, leukemia |
Monocytes | Largest of WBCs |
life span of monocytes | several months |
Monocytosis | Increase in monocytes |
Conditions associated with monocytosis | Viral infection, bacterial and parasitic infections, collagen disease, and cirrhosis |
Monocytopenia | Decrease in monocytes |
Conditions associated with Monocytopenia | prednisone treatment and hairy cell leukemia |
Eosinophils | contains a segmented nucleus, generally no more than 2 lobes |
Life span of eosinophils | 8-12 days |
Eosinophilla | increase in eosinophils |
Eosinophilla is associated with | Allergic reactions, parasitic infections, Addison's disease, Lung and bone cancer |
Eosinopenia | decrease in eosinophils |
Eosinopenia is associated with | Infectious mononucleosis, congestive heart failure, aplastic and pernicious anemia, and hypersplenism |
Basophils | least numerous of WBCs and has a S-shaped nucleus |
Granules of basophils contain | Histamine and heparin |
Basophilla | Increase in basophils |
Basophilla is associated with | Chronic inflammation, leukemia, and hodgkin's disease |
Basopenia | decrease in basophils |
Basopenia is associated with | acute allergic reactions, hyperthyroidism, steroid therapy |