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WBC
White blood test
| Term | Definition |
|---|---|
| Categories of Leukocytes | Granular and nongranular |
| Granular leukocytes | Neutrophils, Eosinopihls, and Basophils |
| Nongranular leukocytes | Lymphocytes and Monocytes |
| Range of Neutrophils | 40%-75% |
| Range of Eosinophils | 1%-6% |
| Range of Basophils | 0%-2% |
| Range of Lymphocytes | 20%-40% |
| Range of Monocytes | 3%-10% |
| Diapedesis | Movement of the WBC through the capillaries |
| Phagocytosis | The engulfing and destruction of pathogens and damaged cells |
| Pus contents | dead leukocytes, dead bacteria, and dead tissue cells |
| Normal value for WBC | 4,500 to 11,000/ mm cubed |
| Suppuration | infected area |
| location of WBC | mostly resides in connective tissue and throughout the body |
| Granular | contains distinct granules in cytoplasm |
| Non-granular | contain few or no granules in cytoplams |
| Leukocytosis | Increase in leukocytes |
| Cause of Leukocytosis | pathological and physiological conditions |
| Pathological conditions are associated w/ | infectious mononucleosis, pneumonia, chicken pox, appendicitis, tonsillitis, hemorrhaging, and Leukemia |
| Physiological conditions are associated w/ | emotional stress, exposure to cold conditions, menstruation, Pregnancy and labor, strenuous exercise |
| Leukopenia | decrease in leukocytes |
| Conditions associated w/ Leukopenia | Cirrhosis, infectious hepatitis, bone marrow depression, chemotherapy, radiation therapy, viral infection |
| Neutrophils | Most common and most numerous WBC |
| First responders | Neutrophils |
| 2 types of Neutrophils | segmented and non-segmented |
| bands or stabs | non-segmented parts |
| Life span of the neutrophil | few days |
| Production of neutrophils | takes place in the bone marrow |
| Amoebic movement | a crawling like movement in which the cell forms temporary projections called pseudopodia to be able to move |
| Pseudopodia | False feet |
| Neutrophilla | increase in neutrophils |
| Neutrophilla is associated w/ | acute bacterial infection infections, parasitic infections, liver disease |
| Neutropenia | Decrease in neutrophils |
| Neutropenia is associated w/ | Acute viral infection, blood diseases, hormone disease, and chemotherapy |
| Location of Neutrophils | moves through veins into tissue |
| Lymphocytes | Smallest and 2nd most common white blood cells |
| Life span of lymphocytes | 2 weeks to several years |
| 3 types of of lymphocytes | B cells, T cells, and natural killer cells |
| Lymphocytosis | Increase in lymphocytes |
| Conditions associated with lymphocytosis | Addison's disease, acute and chronic infections, lymphocytic leukemia, carcinoma, and hypothyriodism |
| Lymphopenia | decrease in lymphocytes |
| Conditions associated with lymphopenia | Aids or HIV infections, cardiac failure, cushing's disease, hodgkin's disease, leukemia |
| Monocytes | Largest of WBCs |
| life span of monocytes | several months |
| Monocytosis | Increase in monocytes |
| Conditions associated with monocytosis | Viral infection, bacterial and parasitic infections, collagen disease, and cirrhosis |
| Monocytopenia | Decrease in monocytes |
| Conditions associated with Monocytopenia | prednisone treatment and hairy cell leukemia |
| Eosinophils | contains a segmented nucleus, generally no more than 2 lobes |
| Life span of eosinophils | 8-12 days |
| Eosinophilla | increase in eosinophils |
| Eosinophilla is associated with | Allergic reactions, parasitic infections, Addison's disease, Lung and bone cancer |
| Eosinopenia | decrease in eosinophils |
| Eosinopenia is associated with | Infectious mononucleosis, congestive heart failure, aplastic and pernicious anemia, and hypersplenism |
| Basophils | least numerous of WBCs and has a S-shaped nucleus |
| Granules of basophils contain | Histamine and heparin |
| Basophilla | Increase in basophils |
| Basophilla is associated with | Chronic inflammation, leukemia, and hodgkin's disease |
| Basopenia | decrease in basophils |
| Basopenia is associated with | acute allergic reactions, hyperthyroidism, steroid therapy |