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Immunology Final
| Term | Definition |
|---|---|
| Innate cells | natural killer, mast, eos, baso, phagocytic |
| Adaptive cells | B cells, T cells |
| Fc fragment crystallization | after cleavage of serum-deprived myeloma IgG fractions with papain |
| IgA | secretory component |
| IgD | signals activation of B-cells |
| Antigen presenting cells | dendritic, macrophage, B cells |
| CD8 cells | cytotoxic T cells |
| T helper cells | help activate B-cells and cytotoxic cells |
| Interferons | induce viral resistance in cells |
| Boyden chamber | used to study cell migration and invasion |
| Mitogens | encourage cells to divide, Pokeweed |
| MHC | surface proteins that recognize foreign molecules, chromosome 6 |
| HLA B27 | associated with ankylosing spondylitis |
| Perforin | pore forming protein on cytotoxic cells |
| FTA-ABS | indirect flourescent antibody technique |
| SDS | denatures proteins in PAGE |
| Protein A | used to purify proteins |
| Northern blot | detects RNA molecules |
| Restriction endonuclease | destroys DNA from invading viruses |
| Paul-Bunnell test | detects mono |
| ASO titer | Todd units |
| TPHA test | detects T. Palladium |
| Most common STD in US | HPV |
| Whooping caugh | B. Pertussis |
| Yeast infection | Candida albicans |
| PAM | N. fowleri |
| Contact lens infections | Acanthamoeba |
| HBV envelope | NTCP |
| HBV first detectable antibody | HBcAg |
| HBV transmission | blood contact |
| Hashimoto | hypothyroidism |
| Intrinsic factor | B12 absorption |
| Sucrose hemolysis and HAM tests | PNH |
| Type I hypersensitivity reaction | immediate |
| Type II hypersensitivity reaction | complement dependent |
| Type III hypersensitivity reaction | excess antigen |
| Type IV hypersensitivity reaction | delayed |
| Lectin | carbohydrate binding proteins |
| Anti-A and anti-B | IgM |
| Amorph | gene that doesn't produce a detectable antigen |
| Elution | removing an antibody attached to an RBC |
| Kell antibodies | react at AHG phase, anti-K most common |
| AIHA | DAT positive |
| Chagas disease | T. Cruzi |
| IgA deficient patients | risk of life-threatening allergic reactions |
| Hydrops fetalis | accumulation of fluid in fetal compartments |
| Iatrogenic blood loss | low HGB/HCT due to frequent blood loss or donations |
| Donath-Landsteiner antibody | cold autoantibody, PCH |