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Immunology Final
Term | Definition |
---|---|
Innate cells | natural killer, mast, eos, baso, phagocytic |
Adaptive cells | B cells, T cells |
Fc fragment crystallization | after cleavage of serum-deprived myeloma IgG fractions with papain |
IgA | secretory component |
IgD | signals activation of B-cells |
Antigen presenting cells | dendritic, macrophage, B cells |
CD8 cells | cytotoxic T cells |
T helper cells | help activate B-cells and cytotoxic cells |
Interferons | induce viral resistance in cells |
Boyden chamber | used to study cell migration and invasion |
Mitogens | encourage cells to divide, Pokeweed |
MHC | surface proteins that recognize foreign molecules, chromosome 6 |
HLA B27 | associated with ankylosing spondylitis |
Perforin | pore forming protein on cytotoxic cells |
FTA-ABS | indirect flourescent antibody technique |
SDS | denatures proteins in PAGE |
Protein A | used to purify proteins |
Northern blot | detects RNA molecules |
Restriction endonuclease | destroys DNA from invading viruses |
Paul-Bunnell test | detects mono |
ASO titer | Todd units |
TPHA test | detects T. Palladium |
Most common STD in US | HPV |
Whooping caugh | B. Pertussis |
Yeast infection | Candida albicans |
PAM | N. fowleri |
Contact lens infections | Acanthamoeba |
HBV envelope | NTCP |
HBV first detectable antibody | HBcAg |
HBV transmission | blood contact |
Hashimoto | hypothyroidism |
Intrinsic factor | B12 absorption |
Sucrose hemolysis and HAM tests | PNH |
Type I hypersensitivity reaction | immediate |
Type II hypersensitivity reaction | complement dependent |
Type III hypersensitivity reaction | excess antigen |
Type IV hypersensitivity reaction | delayed |
Lectin | carbohydrate binding proteins |
Anti-A and anti-B | IgM |
Amorph | gene that doesn't produce a detectable antigen |
Elution | removing an antibody attached to an RBC |
Kell antibodies | react at AHG phase, anti-K most common |
AIHA | DAT positive |
Chagas disease | T. Cruzi |
IgA deficient patients | risk of life-threatening allergic reactions |
Hydrops fetalis | accumulation of fluid in fetal compartments |
Iatrogenic blood loss | low HGB/HCT due to frequent blood loss or donations |
Donath-Landsteiner antibody | cold autoantibody, PCH |