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Hematology
CMA180
| Term | Definition |
|---|---|
| 10 mm/hr | Measures the rate at which anticoagulated RBCs will fall when allowed to settle in a thin columnar tube. The ESR is a nonspecific screening test for inflammatory activity. |
| 12 Seconds | PT: Prothrombin time; an assay that monitors the extrinsic pathway leading to fibrin clot formation. Used to monitor coumadin therapy. |
| 14 g/dL | Hemoglobin (hgb) |
| 200,000/mm^3 | Platelet count |
| 30 Seconds | PTT: An assay that monitors the intrinsic pathway leading to fibrin clot formation. Used to monitor heparin therapy. |
| 4.5 million/mm^3 | |
| 45% | HCT Normal Values (Hematocrit) |
| 8,000/mm^3 | Leukocyte count |
| AB Positive | |
| Anemia | Conditions characterized by a deficiency in quantity or size of RBCs, or hemoglobin content. |
| Anisocytosis | Describes general variation in RBC size. |
| Band Neutrophils | Immature form of the segmented neutrophil requiring a separate classification. |
| Basophils | Large, dark purple to black granules |
| Christmas | Caused by a factor IX deficiency. |
| DIC | A disorder, often triggered by tissue trauma, characterized by massive coagulation that depletes the clotting factors, followed by massive fibrinolysis, which in turn causes severe hemorrhage. |
| Eosinophils | Contains large, red-orange to dirty-pink granules. |
| Erythroblasts Fetalis | AKA hemolytic disease of the newborn (HDN). A potentially fatal hemolytic disease, may occur when an Rh neg mother is pregnant with an Rh pos fetus. |
| Extrinsic | Activation of the coagulation cascade when damaged tissue outside the circulatory system releases factor III into the circulatory system. |
| Fibrinolysis | Initiated to break down the fibrin clot that is formed. |
| Globin | |
| Hematology | Scientific study of blood and blood-forming tissues. |
| Heme | Iron-containing portion of the molecule combines with globin (the protein portion) and forms an activated form of hemoglobin that is ready to transport oxygen. |
| Hemolytic Anemia | Characterized by increased hemolysis of red cells. Often due to transfusion reactions, autoimmune disorders, or fetal blood that is incompatible with maternal blood. |
| Hypertonic | A solution that has a higher concentration of solute outside the cell than inside. This will cause the cell to lose liquid and shrink (crenation). |
| Hypotonic | A solution that has a lower concentration of solute outside the cell than inside. This will create a rush of liquid into the cell causing it to burst (lysis). |
| Instrinsic | Activates the coagulation factors within the blood when endothelial lining of the vessel is damaged. |
| Leukemia | A neoplastic condition characterized by the proliferation of immature leukocytes in the peripheral blood. |
| Lymphocytes | Are produced primarily by the lymphoid tissue (lymph nodes, thymus, and spleen). Smallest normal WBC |
| Megablastic Anemia | Results from a vitamin B12 or folic acid deficiency, or both. |
| Monocytes | Largest normal WBC. |
| Normal Saline | 0.85 g/dl NaCl solution. |
| O Negative | |
| Plasmin | Enzyme responsible for digesting fibrin or fibrinogen. |
| Poikilocytosis | Describes general variation in RBC shape. |
| Polycythemia | Characterized by an excessive production of RBCs. Increased RBC count, hemoglobin, and hematocrit. |
| Rh | Eighty-five percent of the population is pos, 15 percent is neg. |
| Segmented Neutrophil | PMNs (polymorphonuclear neutrophils). Most numerous granulocyte |
| Shift To The Left | Increased numbers of bands. |
| Shift To The Right | Increased numbers of segs. |
| Thrombocytes | AKA platelets. |
| Von Willebrand's | Caused by a factor VIII deficiency. |
Created by:
itsdelis
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