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Nite class

Blood and lymphatic systems

What are WBC called Leukocytes Main function defense
WBC are larger then ? But fewer in numbers Erythrocytes
Mature WBC have a nucleus but Does not have hemoglobin
Plasma is how much percent water 90% water = liquid portion of blood Transports cellular elements of blood through out the circulatory system
Remaining portion of plasma = solutes Most abundant solutes are plasma proteins 3 different kinds 1 albumins 2 globulins 3 fibrinogen Also electrolytes fats glucose bilirubin and gases
two parts of blood plasma / formed elements
Albumins Constitute 60% of the plasma proteins Keep us at a normal balance Help maintain normal blood pressure Maintain balance between fluid in the blood and in the interstitial tissues ( clear yellowish fluid)
Globulins Constitute 36 % of plasma proteins 1 alpha 2 beta globulins transport lipids (fats) And fat soluble vitamins in blood 3 gamma globulins are antibodies and function in immunity
IGG Past infection titers
IGM Active currant infection
IGE Allergies
IGA Digestive track
Thrombus Stationary clot
Embolis Traveling clot
Red blood cells Erythrocytes Life span 120 days Tiny biconcaved -shaped disks Main component = hemoglobin Transports oxygen to cells of the body
Mature RBC is Anucleate ( no nucleus)
Leukocytes Mature WBC has a nucleus / does not have hemoglobin
Two categories of WBC Granulocytes have granules in there cytoplasm Agranulocytosis have no granules in there cytoplasm 5 different types of Leukocytes
# 1 Neutrophils Neutrophils 60/70 % of all WBC Pathagocytic in nature eating and destroying / fights bacteria
# 2 eosinophils 2/4 % of all WBC For allergic reaction
#3 basophils Less then 1% of WBC Secret histamine during allergic reaction Secrete heparin a natural coagulate
Agranulocytes / monocytes Paceman 3/ 8% WBC Largest of WBC macrophages eats pathogens and cellular debri Kidney bean shape nucleus pathogenic in nature ( eats)
Agranulocytes / lymphocytes 20/25% WBC Fights viruses Large spherical- shaped nucleus Immune process They are phagocytic / T cells / helpers / killers memory Produce antibodies
Cell fragments Thrombocytes Also called platelets Small dicc- shaped fragments of a very large cell called (MEGAKARYOCYTES) No hemoglobin / essential for coagulation
Universal donor blood Type (O-) No antigens (A or B) present on its RBC
Universal recipient blood type Type AB positive (AB+) No A or B antigens present in plasma
Coagulation Clotting of blood
1 Injury to blood vessel creates roughened area in vessel 2 platelets come in contact with fought spot and disintegrate Releases substance called thromboplastin
3 thromboplastin converts prothrombin into thrombin 4 thrombin convert fibrinogen into fibrin 5 thrombin threads a mess that forms a clot
Anemia W/O blood abnormal level of hemoglobin Resulting in oxygen decrease/ deficiency in cells Fatigue / paleness/ headache/
Aplastic anemia W/O formation pancytopenia ( all cells decreased) Bone marrow depression RBC WBC platelets all decreased
Enzyme -linked immunosorent assy Blood test used for screening for antibody to AIDS VIRUS Also lime disease
Western blot Western bolt test Detects the presence of the antibodies for HIV the virus AIDS used to confirm validity by ELISE test
Schilling test A diagnostic analysis for pernicious anemia
Hemoglobin test Concentration measurements of the hemoglobin in the peripheral blood
Bleeding time Measurement of time required for bleeding to stop
Coombs test / direct anti- globulin test Test used to discover the presence of antierythrocyte antibodies present in the blood of an RH - neg woman and RH incompatibility between a pregnant RH - woman and her RH+ fetus
Sickle cell Chronic hereditary form of hemolytic anemia RBC become crescent shaped in the presence of low oxygen RBC clump together forming thrombosis
Lymphangiogram X- Ray assessment of the lymphatic system by injecting contrast mending into hands or foot
Mononucleosis A benign self limiting acute infection of the B lymphocytes caused by EBV
Myasthenia gravis Autoimmune disease antibodies block / destroy some acetylcholine Receptor site / muscle weakness
Hemolytic anemia A form of anemia extreme reduction in circulating RBC due to there destruction
Multiple myeloma Malignant plasma cell neoplasm in form of pinpoint hemorrhages and inmature plasma cells often entirely replace bone marrow and destroy the skeletal structure
gradulocytosis anemia Elevated number of granulocytes / circulating blood as a reaction to inflamotory or infection
Leukemia Excessive uncontrolled increase of immature WBC in the blood Leading to infection anemia and thrombocytopenia
Purpura Collection of blood beneath the skin in form of pinpoint hemorrhages red Purpura skin discoloration
Pernicious anemia Anemia resulting from a deficiency of MATURE RBC / formation of circulation Of megaloblasts marked with poikiloctosis and antiocytosis
Hemophilia Hereditary inadequacies coagulation resulting in prolonged bleeding times
Kaposi's sarcoma Locally destructive malignant neoplasms of the blood vessels Associated with AIDS. Leasions on skin. Visit rica organs mucous membranes
Lymphoma Lymphoid tissues neoplasm maglignant painless enlarged lymph nodes followed by anemia weakness fever weight loss
PCP Worldwide parasites
Aplastic anemia bone marrow depression anemia / pancytopenia / inadequacy of formed blood elements ( RBC and WBC and platelets)
Polycythemia Vera Abnormal proliferation of RBC / granulocytes / thrombocytes leading to an increased volume and viscosity (thickness)
Systematic lupus erythermatosus Inflammatory connective tissue disease chronic in nature Immune complexes are formed from reaction SLE autoantibodies
Acquired immunodeficiency Last or final phase of a human immunodeficiency virus HIVdamages T cell lymphocytes with CD 4 receptors
CMV Cytomegalovirus virus
ARC AIDS related complex
EBV Epstein bar virus
ITP Idiopathic thrombocyte penic Purpura
AIDS Acquired immunodeficiency syndrome
HSV Herpes simplex virus
HIV Human immunodeficiency virus
SLE Systemic lupus erythermatosus
KS Kaposis sarcoma
PPT Blood test used to assess clotting proficiency factor 1 and 2 Fibrinogen and prothrombin factors 5 8 9 10 11 12
Agranulocytes Large nucleus kidney bean shaped
Lypmphocytes Large spherical shape nucleus / immune /attack bacteria
Thrombocytes Know as platelets / small disc- shaped fragments of a very large cell Called MEGAKARYOCYTES
Antigens Also called agglutinogen/ RBC Antigens make antibodies
Antibodies After mature go after antigens - attack
Matching antigens and antibodies test For blood donor test called blood typin& cross match
Agglutination Firmly stick or be stuck together to form a mass
Created by: Tbella



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