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Haemopoiesis

Describe how the various types of blood cell are derived from a common progenit

QuestionAnswer
What is haemopoiesis? The production of blood cells and platelets, which occurs in the bone marrow.
What is haemopoiesis also known as? Haematopoiesis
What are all cellular blood components derived from? Haematopoietic stem cells
Where do haemopoietic stem cells reside? What do they have the unique ability to do? Haematopoietic stem cells (HSCs) reside in the medulla of the bone (bone marrow) and have the unique ability to give rise to all of the different mature blood cell types and tissues
What type of cells are HSCs? What happens when they proliferate? self-renewing cells: when they proliferate, at least some of their daughter cells remain as HSCs, so the pool of stem cells is not depleted
Can myeloid and lymphoid progenitor cells renew themselves? No
What two groups to all blood cells belong to? The myeloid group or the lymphoid group
What two types of cell are in the lymphoid group? T-lymphocytes and B-lymphocytes
In adults where does haemopoiesis occur? Bone marrow and lymphatic tissues
What are all types of blood cell derived from (generally)? Primitive cells (stem cells) that are pluripotent (they have the potential to develop into all types of blood cells)
Which bones specifically is haematopoiesis happening in? Flat bones/irregular flat bones - e.g. pelvis and sternum
What do haematopoietic stem cells differentiate slightly to form? Either a myeloid progenitor or a lymphoid progenitor
After childhood what happens to the thymus? Degenerates
Created by: Aimee76
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