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Red Blood Cells
Briefly describe the structural and molecular features of the red blood cell and
Question | Answer |
---|---|
What are globulins? | Protein group to which antibodies belong |
How long do RBCs circulate for before they are removed? | 120 days |
What shape are RBCs? | Biconcave disc shaped |
What does their shape give RBCs? | A large surface area in relation to their volume |
How big is the RBCs nucleus? | They don't have one lol |
What does the flexibility of the RBCs cell membrane allow? | allows the cell to easily squeeze through normal capillaries Although a red blood cell is wider than some capillaries, its flexibility allows it to become distorted as it squeezes through narrow passages and then restores to its original shape. |
Why do RBCs have no nucleus or sub-cellular organelles? | RBCs have no nucleus or any other sub-cellular organelles - this leaves maximum space for the respiratory pigment haemoglobin (dark red) |
What structural thing makes the RBC so flexible? | Inner surface contains actin - makes them flexible |
Where are RBCs produced and by what process? | RBCs are produced in body marrow by the process of erythropoiesis |
What process are RBCs produced by? | erythropoiesis |
How is oxygen transported in the blood? | Oxygen is transported joined to haemoglobin as oxyhaemoglobin (bright red) |
What else can haemoglobin carry? | O2 |
What may the number of RBCs vary with? | The number of red blood cells may vary depending on geographical location – a person who lives in high altitudes will have more red blood cells. |
What does a RBC lack? | Nucleus, mitochondria and endoplasmic reticulum |
What allows RBCs to produce small amounts of energy? | enzymes within the RBCs allow it to produce small amounts of energy (ATP from glucose) |
What is the functional component of RBCs? | Haemoglobin |
What is the stimulus for producing RBCs? | Hypoxia (low oxygen state) |
As well as hypoxia what else needs to be there to stimulate the production of RBCs? | However, hypoxia alone will not be sufficient to trigger the production of new red blood cells unless the hormone erythropoietin is circulating in the bloodstream |
What is the hormone erythropoietin produced by? | Kidneys |
What happens to RBCs rather than being actively removed and where does this primarily happen? | Most of the red blood cells self destruct rather than being actively removed from the circulation and destroyed. The primary site where this occurs is in the spleen |