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Blood components
Blood components and functions
| Question | Answer |
|---|---|
| What is blood classified as and what does it consist of? | Blood is classified as a connective tissue and it consists of two main components |
| What components does blood consist of? | Plasma and formed elements |
| What is plasma? | Plasma is a clear extracellular fluid |
| What are formed elements made up of? | Platelets and blood cells |
| Why are formed elements so called? | So named because they are enclosed in a plasma membrane and have a definite structure and shape |
| What are platelets? | tiny fragments of bone marrow cells |
| Which three things are classed as formed elements? | 1. Erythrocytes, aka RBCs 2. Leukocytes, aka WBCs 3. Platelets |
| Give two types of WBCs | Granulocytes and Agranulocytes |
| Name the types of granulocytes | Neutrophils Eosinophils Basophils |
| Name the types of agranulocytes | Lymphocytes Monocytes |
| What are granulocytes? | cells with prominent granules and a multilobed nuclei |
| What are agranulocytes? | nongranular cytoplasm with non lobed nucleus |
| What type of WBC is a neutrophil and what is it's function? | Granulocyte, Phagocytosis of pathogenic microorganisms (innate immune system) |
| What type of WBC is a basophil and what is it's function? | Granulocyte, Capable of ingesting foreign particles. Secretes heparin, serotonin and histamine which intensifies the inflammatory response |
| What type of WBC is an eosinophil and what is it's function? | Can ingest foreign particles, secrete "major basic protein" which is involved in the defence against certain parasitic worms |
| What type of WBC is a lymphocyte and what is it's function? | Agranulocyte, Subdivided into B-lymphocytes and T-lymphocytes B lymphocytes produce circulation antibodies T lymphocytes produce long term immunity and are capable of destroying cells infected with a particular antigen |
| What type of WBC is a monocyte and what is it's function? | Agranulocyte, Migrate out of blood to form macrophages - phagocytic cells which engulf bacteria and all debris |
| List three functions of blood | Protection, Inflammation and Regulation |
| Describe the role of blood for protection | • Blood has the ability to clot; this protects the body from excessive blood loss • WBCs in the blood help to fight infection by producing antibodies and the phagocytosis of bacteria |
| Describe the role of blood in inflammation | • Leukocytes, or WBCs, destroy invading microorganisms and cancer cells • Antibodies and other proteins destroy pathogenic substances • Platelet factors initiate blood clotting and help minimise blood loss |
| Describe the role of blood in regulation | Blood helps regulate body temperature as the plasma can absorb heat and then be lost to the environment as the blood flows closer to the skins surface |
| Describe the role of blood in regulation | • Blood also regulates pH in the body by acting via buffers • The osmotic pressure of blood also allows the water content of cells to be maintained |
| What is plasma a mixture of? | Plasma is a mixture of proteins, enzymes, nutrients, wastes, hormones and gases |
| What do plasma proteins serve as? | Plasma proteins serve as carriers for other molecules |
| What is the most abundant substance in plasma? | Proteins are the most abundant substance in plasma by weight |
| How long do platelets live? | 5-9 days |
| What do platelets contain? | They contain many granules but no nucleus |
| What do platelets promote and how? | Vascular spasm and blood clotting by releasing the chemicals ADP, serotonin and thromboxane A2 |
| List the components of plasma | Water, Albumins (proteins), Globulins (protein), Electrolytes, Nutrients, Gases, Wastes, Fibrinogen (protein) |
| What is fibrinogen produced by and what is it essential in? | Liver, clotting |
| What is transported in the plasma? | Enzymes and hormones |
| What do albumins act as? | A transport protein for many steroid hormones and fatty acids |
| neutrophils | phagocytosis |
| basophils | can ingest foreign particles |
| eosinophil | secretes 'major basic protein' and ingests foreign particles |