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Chapter 13
Endocrine system
| Endocrine system | Helps nervous system with communication and control of the body |
| Endocrine glands | Cells tissues and organs |
| Quasi endocrine | Paracrine and autocrine glands |
| Endocrine Gladys communicate by | Chemical signals |
| General characteristics of endocrine system | Neurons release neurotransmitters into a synapse affecting post synaptic cells |
| Chemical signal | Neurotransmitter hormone |
| Cells | Neurotransmitter glandular epithelium |
| Specificity of action | Receptors on post synaptic cell receptor on target cell |
| Speed of onset | Seconds to hours |
| Duration of action | Very brief unless neuronal activity continues may be brief or my last ayes even if secretion ceases |
| Larger endocrine glands | Pituitary gland thyroid gland pathyroid glands adrenal glands pancreas |
| Hypothalamus | Corticotropin releasing hormone gonadotropin releasing hormone somatostatin growth hormone prolactin release inhibiting hormone prolactin release factor thyrotropin releasing hormone |
| Anterior pituitary gland | Adrencarticatropic hormone follicle stimulating hormone growth hormone luteinizing hormone prolactin thyroid stimulating hormone |
| Posterior pituitary gland | Antidiuretic hornmone oxycocin |
| Thyroid gland | Calcitonin thyroxine trilothyronine |
| Parathyroid gland | Parathyroid hormone |
| Adrenal medulla | Epinephrine norepinephrine |
| Adrenal cortex | Aldosterone cortisol |
| Pancreas | Glucagon insulin somatostatin |
| Steroid abuse | Drop in natural testosterone heart and liver damage breast development in males behavior changes |
| Growth hormone | Used with steroids usually joint pain swelling hard to detect |
| Erythropoietin | Red loading by a hormone produced by the kidneys which stimulates more rbc production heart attacks |
| Control of hormonal secretion | Primary controlled by negative feedback mechanism |
| Prostaglandins | Paracrine substance potent in small amounts |
| Anterior lobe front | Adenohypophysis hypothalamic releasing hormones stimulate cells |
| Posterior lobe back | Neurohypophysis neurosecretory cells extending from hypothalamus release hormones into bloodstream |
| Hypothalamus (1) | Releasing hormone 1, anterior pituitary 2, peripheral endocrine gland 3 last is target cells |
| Growth hormone gh | Stimulates increase in size and rate of division of body cells enchanes movement of amino acids through membranes promotes growth of long bones |
| Prolactin prl | Sustained milk production after birth amplified the effect of lh in males |
| Thyroid stimulating hormone tsh | Controls secreation of homones from thyroid gland |
| Adrerenocorticotropic hormone acth | Controls secreation of hormones from the adrenal cortex |
| Follicle stimulating hormone fsh | Development of egg containing follicles in ovaries stimulates follicular cells to secrete estrogen in males. Stimulates production of sperm cells |
| Luteinizing hormone lh | Promotes secretion f sex hormones releases egg cell in females |
| Antidiuretic hormone adh | Causes kidneys to reduce water excreation in high concentration raises blood pressure |
| Oxytocin ot | Contracts muscles in uterine wall and those associated with milk secreation glands |
| Thyroid gland produces | T4 thyroxine T3 triiodothyronine and calcitonin |
| Type 1 diabetes juvenile | Autoimmune disorder where pancreatic beta cells are destroyed halting insulin production |
| Type two diabetes | Cells lose functional insulin receptors and therefore less able to respond to insulin |
| Type 3 | Gastroentril diabetes pregnancy |