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Chapter 18
The Cardiovascular System - Cardiac Cycle, ECG's, Intrinsic Conduction System
| Question | Answer |
|---|---|
| pacemaker cells set the pace, one special thing about them is: | they can spontaneously depolarize |
| this type of cell has an unstable resting potential. | pacemaker cells |
| ___ causes depolarization | calcium |
| what is the pacemaker of the heart? | SA node |
| 3 steps of the cardiac action potentials. | pacemaker potential -> depolarization -> repolarization |
| what happens in the pacemaker potential? | the K+ channels close because of the opening of Na+ channels |
| in the depolarization phase the pacemaker potential __ | reaches threshold - calcium causes depolarization |
| due to calcium channels and potassium channels opening the membrane potential goes back to negative voltage. this is because of __ | repolarization |
| what is the fastest depolarization rate? | SA node |
| this sets the rhythm via sinus rhythm & has the fastest depolarization rate | SA node |
| step 1 of the intrinsic conduction system | SA node generates impulses |
| after the SA node generates impulses. what happens? | the wave spreads through the atrium to AV node |
| why is there a delay when the wave spreads from the atrium to AV node? | because the muscle fibers are so small |
| step 3 of the intrinsic conduction system | the AV bundle connects the atria to the ventricle |
| after the AV bundle connects the atria to the ventricle, the ___ and lastly the __ | bundle branches conduct impulses to the inter-ventricular septum - the punkinje fibers connect |
| when the pukinje fibers network it: | spread impulses to both ventricles, depolarizing the cells |
| there are no gap junctions connecting the __ and __ | atria - ventricles |
| what is the purpose of the AV node/? | it slows down impulses so contraction can occur |
| depolarization | contracting |
| repolaruzation | relaxing |
| what is an electrocardiogram (ECG) | graphic record of the electrical activity of the heart |
| sequence of events when the atria & ventricles are contracting or relaxing is known as the: | cardiac cycle |
| diastole refers to __, while systole refers to __ | relaxation - contraction |
| heart murmur | abnormal heart sounds that results from valve problems |
| condition of rapid & irregular heart contractions | fibrillation |
| what are the 3 steps of the cardiac cycle? | ventricular filling (mid to late diastole) ventricular systole early diastole |
| in ventricular filling (mid-to-late diastole) what happens? | atrial contracts --> pumps blood to ventricle |
| during the ventricular filling the __ stays open allowing: | mitral valve - blood to move in |
| the ventricular systole is known as the ___ phase. during this phase no ___ . after this phase the ___ occurs | isovolumetric contraction - blood has left yet - ventricular ejection |
| in the early diastole ___ occurs. the ventricular filling then begins to open the __ and __ | relaxation - AV valve , pushes blood to large ventricles |
| the semilunar valve closes during which step of the cardiac cycle? | early diastole |
| the lub sound comes from the: | AV valves closing |
| the dub sounds come from the: | SV valves closing |
| arrythmias are __ | irregular heart rhythms |
| extrasystole is a __ contraction | premature |
| ectopic pacemakers with functional SA nodes can lead to: | extrasystole |
| in defective SA nodes when the pacemaker is abnormal, what happens? | the AV node becomes pacemaker |
| ___ can cause uncoordinated atrial & ventricular contractions | arrythmias |
| heart block occurs when __ | there is damage to intrinsic network |
| 5 distinct characteristics in cardiac muscle thats not in skeletal. | no muscle spasms. extracellular fluid involved -> triggers calcium release. self excitable. heart contracts as a unit. heart relies on aerobic respiration (lots of mitochondria - resistance to fatigue) |
| unlike skeletal muscles, cardiac cells can be__ | autorhythmic |
| in cardiac cells, the heart contracts as a unit due to : | gap junctions |
| muscle spasms cannot occur in cardiac muscles because... | the refractory period is the same as contraction |
| atrial diastole occurs at__ | QRS point |
| isovolumetric contraction & ejection are apart of: | systole |
| in isovolumetric contraction, what is happening? | no blood is leaving the heart - just pressure building up |
| in isovolumetric both valves are __ so the volume is ___ | closed - constant, just increasing pressure |
| continued contraction and increase in pressure forces aortic valve to open & cause: | ejection |
| isovolumetric relaxation and filling deals with: | diastole |
| what happens at the P point of an ECG? | atrial depolarization - systole starts |
| what happens at the QRS point of an ECG? | ventricular depolarization - beginning of ventricular contraction |
| at the T point of an ECG, ventricular ___ takes place | repolarization |
| ventricles are depolarized at the ___ segment | ST |
| at the PR segment, atrial __ and ___ takes place | depolarization & AV node conduction |
| condition of rapid & irregular heart contractions | fibrillation |
| in fibrillation, blood vessels ___ | aren't coordinated enough to deliver blood |
| aorta is the __ | major systemic artery - arises from left ventricle of heart |
| heart murmurs are common in: | children |
| the amount of blood pumped out of the ventricles to the body per minute is: | cardiac output |
| the heart rate is set by the__ | SA node |
| heart rate units: | beats/min |
| stroke volume units: | ml/beat |
| the normal stroke volume is__ | 70 ml/beat |
| maximum amount of blood AFTER contractions is known as: | End systolic volume (ESV) |
| End diastolic volume (EDV) | maximum amount of blood BEFORE contractions |
| cardiac output = | heart rate x stroke volume |
| the amount of blood pumped out of your heart with each heartbeat is known as__ | stroke volume |
| average adult CO | 75 beats/min (5.25L/min) |
| cardiac output has a direct relationship with __ | heart rate & stroke volume |
| the volume pumped by each ventricle is the same, however.... | the pressure is different |
| pressure is higher in which ventricle?" | left |
| how do you calculate stroke volume? | EDV-ESV |
| EDV is determined by __ | length of ventricular diastole & venous return |
| ESV is determined by ___ | arterial blood pressure & force of ventricular contraction |
| ESV is usually __ ml | 50 |
| EDV is usually __ ml | 120 |
| frank-starling law states: | the greater the stretch, the greater the SV |
| preload is the degree to which cardiac muscle has stretched __ contarction | before |
| preload means increase in __ which means increase in __ | EDV - SV |
| low venous return results from __ | blood loss of rapid heart rate - doesn't allow time for ventricular filling |
| excersise __ venous return through sympathetic activation & __ | increases - squeezing action of skeletal muscles on veins |
| more calcium that enters, __ the contractions | stronger |
| increase in contractility means ___ | more blood is ejected, ESV decreases while SV increases |
| afterload is normally __ mmHg in the aorta | 80 |
| the CAC and CIC are located where? | medulla |
| the cardioaccelatory system (CAC) is more global, therefore it talks to the __ while the cardioinhibitory system (CIC) talks to the __ | SA node, AV node and other parts of heart - SV & AV nodes |
| the CAC can effect ___, while the CIC effects the __ | contractility - heart rate |
| exercise acts through the __ nervous system | sympathetic |
| baroreceptors respons to : | blood pressure changes |
| blood pressure changes when __ changes | cardiac output |
| atrial reflex is initiated by: | increase in venous return |
| when one autonomic division is activated by sensory input, the other is ___ | temporarily inhibited |
| what is contractility? | muscle cells ability to move by shortening |