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Chapter 18
The Cardiovascular System - Cardiac Cycle, ECG's, Intrinsic Conduction System
Question | Answer |
---|---|
pacemaker cells set the pace, one special thing about them is: | they can spontaneously depolarize |
this type of cell has an unstable resting potential. | pacemaker cells |
___ causes depolarization | calcium |
what is the pacemaker of the heart? | SA node |
3 steps of the cardiac action potentials. | pacemaker potential -> depolarization -> repolarization |
what happens in the pacemaker potential? | the K+ channels close because of the opening of Na+ channels |
in the depolarization phase the pacemaker potential __ | reaches threshold - calcium causes depolarization |
due to calcium channels and potassium channels opening the membrane potential goes back to negative voltage. this is because of __ | repolarization |
what is the fastest depolarization rate? | SA node |
this sets the rhythm via sinus rhythm & has the fastest depolarization rate | SA node |
step 1 of the intrinsic conduction system | SA node generates impulses |
after the SA node generates impulses. what happens? | the wave spreads through the atrium to AV node |
why is there a delay when the wave spreads from the atrium to AV node? | because the muscle fibers are so small |
step 3 of the intrinsic conduction system | the AV bundle connects the atria to the ventricle |
after the AV bundle connects the atria to the ventricle, the ___ and lastly the __ | bundle branches conduct impulses to the inter-ventricular septum - the punkinje fibers connect |
when the pukinje fibers network it: | spread impulses to both ventricles, depolarizing the cells |
there are no gap junctions connecting the __ and __ | atria - ventricles |
what is the purpose of the AV node/? | it slows down impulses so contraction can occur |
depolarization | contracting |
repolaruzation | relaxing |
what is an electrocardiogram (ECG) | graphic record of the electrical activity of the heart |
sequence of events when the atria & ventricles are contracting or relaxing is known as the: | cardiac cycle |
diastole refers to __, while systole refers to __ | relaxation - contraction |
heart murmur | abnormal heart sounds that results from valve problems |
condition of rapid & irregular heart contractions | fibrillation |
what are the 3 steps of the cardiac cycle? | ventricular filling (mid to late diastole) ventricular systole early diastole |
in ventricular filling (mid-to-late diastole) what happens? | atrial contracts --> pumps blood to ventricle |
during the ventricular filling the __ stays open allowing: | mitral valve - blood to move in |
the ventricular systole is known as the ___ phase. during this phase no ___ . after this phase the ___ occurs | isovolumetric contraction - blood has left yet - ventricular ejection |
in the early diastole ___ occurs. the ventricular filling then begins to open the __ and __ | relaxation - AV valve , pushes blood to large ventricles |
the semilunar valve closes during which step of the cardiac cycle? | early diastole |
the lub sound comes from the: | AV valves closing |
the dub sounds come from the: | SV valves closing |
arrythmias are __ | irregular heart rhythms |
extrasystole is a __ contraction | premature |
ectopic pacemakers with functional SA nodes can lead to: | extrasystole |
in defective SA nodes when the pacemaker is abnormal, what happens? | the AV node becomes pacemaker |
___ can cause uncoordinated atrial & ventricular contractions | arrythmias |
heart block occurs when __ | there is damage to intrinsic network |
5 distinct characteristics in cardiac muscle thats not in skeletal. | no muscle spasms. extracellular fluid involved -> triggers calcium release. self excitable. heart contracts as a unit. heart relies on aerobic respiration (lots of mitochondria - resistance to fatigue) |
unlike skeletal muscles, cardiac cells can be__ | autorhythmic |
in cardiac cells, the heart contracts as a unit due to : | gap junctions |
muscle spasms cannot occur in cardiac muscles because... | the refractory period is the same as contraction |
atrial diastole occurs at__ | QRS point |
isovolumetric contraction & ejection are apart of: | systole |
in isovolumetric contraction, what is happening? | no blood is leaving the heart - just pressure building up |
in isovolumetric both valves are __ so the volume is ___ | closed - constant, just increasing pressure |
continued contraction and increase in pressure forces aortic valve to open & cause: | ejection |
isovolumetric relaxation and filling deals with: | diastole |
what happens at the P point of an ECG? | atrial depolarization - systole starts |
what happens at the QRS point of an ECG? | ventricular depolarization - beginning of ventricular contraction |
at the T point of an ECG, ventricular ___ takes place | repolarization |
ventricles are depolarized at the ___ segment | ST |
at the PR segment, atrial __ and ___ takes place | depolarization & AV node conduction |
condition of rapid & irregular heart contractions | fibrillation |
in fibrillation, blood vessels ___ | aren't coordinated enough to deliver blood |
aorta is the __ | major systemic artery - arises from left ventricle of heart |
heart murmurs are common in: | children |
the amount of blood pumped out of the ventricles to the body per minute is: | cardiac output |
the heart rate is set by the__ | SA node |
heart rate units: | beats/min |
stroke volume units: | ml/beat |
the normal stroke volume is__ | 70 ml/beat |
maximum amount of blood AFTER contractions is known as: | End systolic volume (ESV) |
End diastolic volume (EDV) | maximum amount of blood BEFORE contractions |
cardiac output = | heart rate x stroke volume |
the amount of blood pumped out of your heart with each heartbeat is known as__ | stroke volume |
average adult CO | 75 beats/min (5.25L/min) |
cardiac output has a direct relationship with __ | heart rate & stroke volume |
the volume pumped by each ventricle is the same, however.... | the pressure is different |
pressure is higher in which ventricle?" | left |
how do you calculate stroke volume? | EDV-ESV |
EDV is determined by __ | length of ventricular diastole & venous return |
ESV is determined by ___ | arterial blood pressure & force of ventricular contraction |
ESV is usually __ ml | 50 |
EDV is usually __ ml | 120 |
frank-starling law states: | the greater the stretch, the greater the SV |
preload is the degree to which cardiac muscle has stretched __ contarction | before |
preload means increase in __ which means increase in __ | EDV - SV |
low venous return results from __ | blood loss of rapid heart rate - doesn't allow time for ventricular filling |
excersise __ venous return through sympathetic activation & __ | increases - squeezing action of skeletal muscles on veins |
more calcium that enters, __ the contractions | stronger |
increase in contractility means ___ | more blood is ejected, ESV decreases while SV increases |
afterload is normally __ mmHg in the aorta | 80 |
the CAC and CIC are located where? | medulla |
the cardioaccelatory system (CAC) is more global, therefore it talks to the __ while the cardioinhibitory system (CIC) talks to the __ | SA node, AV node and other parts of heart - SV & AV nodes |
the CAC can effect ___, while the CIC effects the __ | contractility - heart rate |
exercise acts through the __ nervous system | sympathetic |
baroreceptors respons to : | blood pressure changes |
blood pressure changes when __ changes | cardiac output |
atrial reflex is initiated by: | increase in venous return |
when one autonomic division is activated by sensory input, the other is ___ | temporarily inhibited |
what is contractility? | muscle cells ability to move by shortening |