Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Chaney - Exam2

Metabolism

QuestionAnswer
coenzyme small molecular weight metabolites which are neccesary for enz. activity, present in small amounts, and are regenerated by other cellular enz.
ATP carries Phosphoryl
NADH + NADPH carry electrons (vitamin source niacin)
FADH2 + FMNH2 carry electrons (vitamin source riboflavin)
Coenzyme A carries Acyl (vitamin source pantothenic acid)
Lipoamide carries Acyl
Thiamine pyrophosphate carries aldehyde (vitamin source thiamine)
Biotin carries CO2
Tetrahydrofolate carries one-carbon units (vitamin source folic acid)
S-Adenosylmethionine carries methyl
Uridine diphosphate glucose carries glucose
Cytidine diphosphate di glycerol carries phosphatidate
Nucleosome triphosphates carry phosphoryl
insulin decreases blood sugar -increases uptake of glucose(except liver, brain, RBC) -increases glycolysis in liver and adipose -increases conversion of glucose to storage forms
glucagon increases blood sugar + increases release of alternate energy sources -increases gluconeogenesis in liver -increases glycogenolysis in liver -decreases glycolysis in liver -increases lipolysis in adipose
epinephrine mobilizes energy reserves + stimulates energy use in muscle -increases glycogenolysis in liver and muscle -increases lipolysis in adipose -increases proteolysis in muscle -increases gluconeogenesis in liver -increases glycolysis in muscle
GLUT 1 & 3 transport glucose RBC, brain, kidney, colon - allow constant uptake (even at low concentration) due to low Km
GLUT 2 transports glucose in liver, beta cells of pancreas, kidney, small intestine - take up glucose when at high concentration due to very high Km, leads to regulation at high levels of glucose
GLUT 4 transports glucose in an insulin dependant manner in skeletal muscle and adipose tissue
nucleoside kinase adds phosphate to nucleoside for salvage
phosphoribosyl transferase adds phospho-ribo groupd to base for salvage
HGPRTase hypoxanthine-guanine phosphoribosyl transferase - specific for salvage of HX, X, and G bases
Deaminases degrade amino group of purine
nucleotidases degrade phosphate group of purines
nucleoside phosphorylases cleave ribose from purines using Pi
xanthine oxidase degrades purine ring of xanthine to uric acid (2 steps)
Adenylate deaminase deficiency muscle weakness, excercise intolerance
adenosine deaminase SCID
partial deficiency of HGPRTase Gout
hexokinase fixes glucose in the cell, low Km--> works at low concentration
glucokinase fixes and activated glucose in cells with GLUT-2 (liver, beta cells)
PFK rate limiting for glycolysis, enhanced by allosteric regulation of F26BP--> increase affinity for F6P and decreases inhibition by ATP
pyruvate kinase PEP + AMP-->pyruvate +ATP
lactate dehydrogenase pyruvate + NADH + H --> NAD + lactate
pyruvate carboxylase for gluconeogenesis-in mito, pyruvate --> OAA, requires ATP + biotin
PEP carboxykinase gluconeogenesis,OAA-->PEP, requires GTP
FBP reverse of PFK rxn, allosterically inhibited by F26BP
glucose-6-phosphatase produces free glucose, liver has a lot of it!
glycogen phosphorylase glycogenolysis
glycogen synthase work with branching enzyme to make glycogen
Citrate Synthase OAA + acetylCoA condensed --> citric acid, entry point for CAC
alphaketoglutarate dehydrogenase enzyme complex, requires same cofactors as PDH, alphaKG-->succinyl CoA + NADH + CO2
succinylCoA synthetase succinyl Co --> succinate + GDP + CoASH (fairly reversible rxn)
malate dehydrogenase malate-->OAA + NADH (net flow is opposite Keq)
pyruvate dehydrogenase complex (PDH) enzyme complex, gets pyruvate from glycolysis into mito --> acetylCoA + NADH + CO2, cofactors = thiamine, pantothenic acid, riboflavin, niacin
Created by: MouserKat
Popular Medical sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards