Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Pathology 5 and 6
Pathology: Lectures 5 and 6 Renewal and Repair
| Question | Answer |
|---|---|
| When does renewal occur | in cases where we loose our cells naturally (intestines lining, skin, etc..) |
| When is regeneration of cells no longer able to occur | when parenchymal cells are lost |
| What role do endothelial cells play in repair | they participlate in angiogenesis and thus facilitate bring blood flow back to the area |
| What role do PMN's and macrophages play in repair | remove damage tissue and prevent infection |
| What role to parenchymal cells play in repair | regenerate tissues with the primary functional cell type |
| Are parencymal cells found in the heart? | NO |
| What are charactestics of type I collagen | really strong and found in late wound healing |
| Where would you find type IV collagen | in the basement membrane |
| What are 2 traits of type III collagen | found in early wound healing and is fairly weak |
| What happens in Hemostasis | fibrinogen is converted to fibrin |
| What is a provisional matrix | this is an early/temporary cellular matrix that supports cellualr migration. |
| Which collagen type is found in a provisional matrix | type 3 |
| Which cell types are found in granulation tissue | monocytes, plasma cells, and macrophages |
| During re-epithelialization what is occuring | parenchymal cell recovery |
| What structure/cell type is responsible for contraction | myofibroblast |
| What day does contracture usually occur | day 3 |
| Which collagen type helps to regain tissue strength | type I |
| Which type of tissue is vascular, resistent to infection, occurs between inflammation and contracture and secretes collagen? | granular tissue |
| Which type of wound intention lends itself to fibrosis, less dense tissue and poor reapproxiamtion | secondary |
| What are the three major influences on wound repair | Location, nature/amount of ECM, and Blood supply |
| Will the kideny regenerate if there is minimal damage to the ECM | yes |
| Which area of the kidney is most sussceptible to injur | medulla |
| Which process occurs when there is chronic injury to the liver | fibrosis |
| Do glomeruli regenerate | NO |
| How do lung cells regenerate | Type 2 --> Type 1 |
| What does a patchy loss of cells in the heart signify | interstital fibrosis which could lead to cardiomyopathy or ishemic heart disease |
| A difuse loss of cells in the heart signals what | myocardial infarction |
| What type of necrosis follows and MI | coagulative |
| Which type of nuerons have the ability to regenerate | PNS |
| What type of cells do the scarring in the PNS | fibroblast |
| Abnormal/pathologic contractures can cause bowel stricture if they occur where | abdomen |
| A exuberant, disorganized deposition within the dermis that extends beyond the anatomic boundries of of normal sturcture is called what | Keloid |
| Who is at risk for keloids | darker skined indivudals |
| What is excessive scar formation referred to as | hypertrophic scars |
| Which areas are prone to pathologic contractures | palms and shoes |
| Are contractures common following burns | yes |
| What is a pyogenic ganuloma | exuberant overgrowth of granulation tissue |
| When are pyogenic granulomas likely to occur | on the gingiva of pregnant women |
| granulation tissue that extends above the epithelial surface and precludes re-epithelialization is called what | proud flesh |
| What is excessive, persistent fibrosis following an injury or surgical incision called | desmoids |
Created by:
lowryc
Popular Medical sets