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ossification
endonchondral ossification (major form)
| Question | Answer |
|---|---|
| what bone of the body originate as hyaline cartilage | endochondral ossification |
| what bone replaces the cartilage | endochondral ossification |
| cartilage and chondrocytes in the shaft enlarges in what bones? | long bones |
| in long bones the matrix is reduced to | small struts |
| calcified struts isolate the ___ in long bones | chondrocytes |
| chondrocytes die and disintegrate in | long bones |
| bone formation occurs first on the __ | shaft surface |
| cells of the innter layer of the cartilage covering (perichondrium) differentiate into what? | osteoblasts |
| new blood vessels penetrate the cartilage to the ___ | central region |
| what forms an ossification center within the bone? | new osteoblasts |
| spongy bone spreads towards ___ | the end |
| as the bone enlarges, osteoclasts erode the ___ | trabeculae |
| secondary ossification centers from in the ___ | epiphyses |
| epiphyses becomes filled with ___ | spongy bone |
| a thin cap of the original cartilage remains exposed on the ends is called what? | articular cartilage |
| at a metaphysis, a narrow cartilaginous region called the ___ separates the epiphysis from the diaphysis. | epiphyseal cartilage |
| growth in length occurs from the ___ | epiphyseal cartilage |
| cell division produces new cartilage, but at the border with diaphysis, older cartilage is broken down by invading osteoclasts (replaced with bone and medullary cavity expands) | epiphyseal cartilage |
| as long as the epiphyseal cartilage continues to grow the bone will continue to ___ | grow in length |