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Chemoreceptors
Peripheral and central chemoreceptors
Definition | Term |
---|---|
Located beneath ventral surface of medulla near the exit of cranial nerves IX and X | Central chemoreceptors |
Anatomically separate from the medullary respiratory centre | Central chemoreceptors |
Most important sensor in minute-minute control of ventilation | Central chemoreceptors |
Are responsible for around 80% of changes to respiration | Central chemoreceptors |
Respond to [H+] in the CSF | Central chemoreceptors |
Protected by the blood-brain barrier | Central chemoreceptors |
Carbon dioxide is converted into hydrogen ions and bicarbonate by carbonic anhydrase in the CSF | Central chemoreceptors |
Take time to respond to changes in PCO2 | Central chemoreceptors |
Located in the carotid bodies at the bifurcation of the common carotid arteries and within the aortic bodies | Peripheral chemoreceptors |
In humans the carotid bodies are the most important | Peripheral chemoreceptors |
Respond to decreases in arterial PO2, pH and PCO2 | Peripheral chemoreceptors |
Probably important in responding to abrupt changes in PCO2 | Peripheral chemoreceptors |
In the absence of these receptors a subject will lose the ventilatory response to hypoxia | Peripheral chemoreceptors |
These are the only chemoreceptors that are sensitive to PO2 | Peripheral chemoreceptors |
High blood flow for their size, and small arterial-venous O2 difference in spite of having a high metabolic rate | Peripheral chemoreceptors |
Which nerve takes information from the carotid bodies to the medulla? | Glossopharyngeal nerve (CN IX) |
Which nerve takes information from the aortic bodies to the medulla? | Vagus nerve (CN X) |