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Anatomy 12-13
Question | Answer |
---|---|
Blood is composed of what three things? | Cells, fluids, and chemicals |
Function of blood: | to transport substances and maintain a stable environment |
Blood hematocrit: | 45% cells and 55% plasma |
RBC = | erythrocyte |
Biconcave disks that contain one-third oxygen carrying hemoglobin by volume | red blood cells |
oxygen + hemoglobin = | bright red oxyhemoglobin |
darker, deoxygenated blood | deoxyhemoglobin |
Red blood cells discard their _____ during development | nucleas |
red blood cells cannot produce _____ | proteins |
RBC count for males | 4.6 - 6.2 million |
RBC count for females | 4.2 - 5.4 million |
Where are RBCs produced in the fetus? | yolk sac, liver, and splen |
Where are RBCs produced after birth? | red bone marrow |
RBC lifespan | 120 days approx |
What maintains the number of RBCs? | a negative feedback system involving erythropoietin |
Needed for DNA synthesis | B12 and folic acid |
Needed for hemoglobin sythesis | iron |
A deficiency in RBC or quantity of hemoglobin | anemia |
RBCs become damaged over time by passing through _____ | capillaries |
________ in the liver and spleen phagocytize damaged red blood cells | macrophages |
Hemoglobin from the decomposed red blood cells is converted into ____ and ____ | heme / globin |
WBCs are formed from ____ | hemocytoblasts |
5 types of leukocytes (hint: NEBML) | Neutrophils, eosinophils, basophils, monocytes, and lymphocytes |
Function of WBC | protection |
normal WBC count | 5,000-10,000 |
Can be used to help pinpoint the nature of an illness | differential WBC count |
Occurs after an infection when excess numbers of leukocytes are present | leukocytosis |
When there are too few WBCs | leukopenia |
Group of leukocytes with granules present in their cytoplasm when stained | granulocytes |
Red-staining fine cytoplasmic granules and a multi-lobed nucleus | neutrophils |
Neutrophils percentage | 54%- 62% |
Function of neutrophils | phagocytize bacteria, fungi, and some viruses |
Squeezing between cells in blood vessel walls | diapedesis |
Have course granules that stain deep blue and have bilobed nucleus | eosinophils |
Eosinophils percentage: | 1%-3% |
Function of eosinophils | Moderate allergic reactions, defend against certain parasites |
Have fewer granules that stain deep blue | basophils |
Basophil percentage | less than 1% |
Function of basophil | to produce chemicals that increase blood flow to damaged tissues and promote inflammation responses |
Lack granules in cytoplasm | agranulocytes |
Largest blood cells that have oval shaped nuclei | Monocytes |
monocyte percentage: | 3%-9% |
Function of monocyte | phagocytize bacteria and cellular debris |
Long-lived and have a large, spherical nucleaus | lymphocyte |
Lymphocyte percentage | 25-33% |
function of lymphocyte | involved in immunity responses |
platelets AKA | thrombocytes |
platelets are fragments of | megakaryocytes |
Platelets repair damaged vessels by ______ to broken edges | adhering |
Average platelet count | 130,000-360,000 |
clear, straw-colored fluid portion of blood | plasma |
Plasma is mostly ______ | water |
Function of plasma | Transport of nutrients and gases, regulates fluid and electrolyte balance, maintains acid base balance |
maintains the correct osmotic pressure of the plasma | albumin |
transport lipids and fat-soluble vitamins, some are a type of antibody | globulin |
play an important role in blood clotting process | clotting proteins |
regulate and control physiological function | hormones |
stoppage of bleeding | hemostasis |
First step of hemostasis | blood vessel spasm |
Second step of hemostasis | platelet plug formation |
Third step of hemostasis | blood coagulation |
Abnormal clot in vessel | thrombus |
dislodged clot | embolus |
Clumping of RBCs following transfusion | agglutination |
special proteins found on the surface of cells | antigen |
Special protein in the blood plasma that interact with specific antigen | antibody |
Type A | Antigen: A / Antibody: anti-B |
Type B | Antigen: B / Antibody: anti-A |
Type AB | Antigen: both / Antibody: neither |
Type O | Antigen: neither / Antibody: both |
Named after rhesus monkey | RH blood type |
If the RH surface protein is present then... | the blood type is positive |
If the RH surface protein is NOT present, then... | the blood type is negative |
develops in rh-positive fetuses of rh-negative mothers | erythroblastosis fetalis |
Consists of the heart, vessels, capillaries, and veins | Cardiovascular system |
Function of CV system | Supplying oxygen and nutrients and removing waste |
hollow, cone-shaped, muscular pump within the thoracic cavity | heart |
The heart lies in the _______ | mediastinum |
Comprised of a tough outer layer of connective tissue and a more delicate double later sac around the heart | pericardium |
inner layer that covers heart directly | visceral pericardium (epicardium) |
tough outer layer portion of pericardium | parietal pericardium |
The space between the two pericardia is filled with ____________ | serous fluid |
Outermost layer of the heart that consists of connective tissue and contains blood and lymph capillaries | epicardium |
Middle layer of the heart that consists of cardiac muscle and is the thickest layer of the heart wall | Myocardium |
Inner layer of the heart that is smooth and made up of connective tissue and epithelium | endocardium |
Divides the chambers of the heart | septum |
Upper chambers that receive blood returning to the heart | atria |
Lower chambers that pump blood and are thicker | ventricles |
A mass of merging fibers that act as a unit is called a functional _________ | synctium |
Specialized mass of of cardiac muscle that generates impulses for the heartbeat | SA node |
Impulses spread next to the atrial ________, it contracts, and impulses travel to the junctional fibers leading to the ___________ node located in the septum | synctium / atrioventricular |
__________ fibers are small, allowing the atria to contract before the impulse spreads rapidly over the ventricles | junctional |
Branches of the AV bundle give rise to ______ fibers leading to papillary muscles. These fibers stimulate contraction of the papillary muscles at the same time the ventricles contract | Purkinje |
The first wave, the P wave, corresponds to the _____ of the atria | depolarization |
The ____ complex corresponds to the depolarization of ventricles and hides the repolarization of atria | QRS |
The T waves end the ECG pattern and correspond to ventrical _______ | repolarization |
The SA node is innervated by branches of the _______ and _______ divisions, so the CNS controls the heart rate | sympathetic and parasympathetic |
Sympathetic ____ impulses | speed up |
parasympathetic ________ heart rate | slow down |
The cardiac control center of the _____ _______ maintains balance between the two autonomic divisions of the nervous system in response to messages from barareceptors | medulla oblongata |
Detect changes in blood pressure | barareceptors |
Impulses from the _____ and _____ may also influence heart rate, as well as temperature and concentrations of certain iions | cerebrum and hypothalamus |
Strong, elastic vessels adapted for carrying high-pressure blood | arteries |
arteries divide into _____ | arterioles |
Provide support and attachment for the heart valves and fibers and keep the tissue from dilating | rings of dense connective tissue |
Alternate pathways for blood if one is to become blocked | anastomoses |
Cardiac veins drain blood from the heart muscle and carry it to the _____ ______ | coronary sinus |
atria beating in unison | atrial systole |
ventricles rest | diastole |
Contraction of both ventricles | ventricular systole |
smooth muscle of an artery | tunica media |
connective tissue of an artery | tunica externa |
When arteries shrink as directed by sympathetic impulses | vasoconstriction |
When impulses are inhibited and arteries widen | vasodilation |
smallest vessels consisting of only a layer of endothelium through which substances are exchanged with tissue cells | capillaries |
Areas with a great deal of metabolic activity have ______ _______ of capillaries | higher densities |
Can regulate the amount of blood entering a capillary bed and are controlled by oxygen concentration in the area | Precapillary sphincters |
Why do plasma proteins remain in the blood? | Because of their larger size |
Drives the passage of fluids and very small molecules out of capillaries | hydrostatic pressure |
Collect excess tissue fluid and return it to circulation | lymphatic vessels |
Force of blood against the inner walls of blood vessels | blood pressure |
Factors that influence blood pressure | heart action, blood volume, resistance to flow, and blood viscosity |