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AP1-Chapter 3
notes part 2
Question | Answer |
---|---|
what is a mutation? | change in the nucleotide sequence of gene |
what two things can a mutation cause? | cancer and blood disorders |
what are the three causes of mutations? | exposure to chemicals and radiation or mistakes during DNA replication |
what goes into the cell membrane? | nutrients |
what must go out of the cell membrane? | waste |
what is permeability? | determines which substances can enter and leave the cytoplasm |
what does impermeable mean? | NOTHING goes in out |
what does freely permeable mean? | ANYTHING goes in and out |
what does selectively permeable mean? | only certain things can move in and out |
which type of cell membrane do we have? | selectively permeable |
what are the four things that can be affected by selective permeability? | size; electrical charge; molecular shape; lipid solubility |
what are the two types of transport? | active and passive |
what is needed in active transport? | energy and ATP |
what is the difference with passive transport? | no energy is required |
what are the tree categories of transport? | diffusion (passive), carrier mediated (can be either), vesicular (active) |
what is diffusion? | movement of area of high concentration to low concentration |
what is the goal of diffusion? | balance |
what is the concentration gradient? | difference between high and low concentration |
what is concentration? | amount of solute in a solvent |
what five factors affect diffusion rate? | distance needed to move, molecule size, temperature, gradient size, electrical forces |
what are the two ways diffusion can be? | simple and channel-mediated |
what is simple diffusion? | materials which diffuse through cell membrane (ex. lipid soluble compounds like alcohols, fatty acids, steroids, and dissolved gases ) |
what us channel mediated diffusion? | materials that must pass through a transmembrane protein channel |
what three things affect passage in channel mediated diffusion? | size, charge, and interaction with the channel |
diffusion of water across a cell membrane | osmosis |
what occurs across a selectively permeable membrane in osmosis | the membrane must be freely permeable to water, but selectively permeable to solutes. |
where does water flow during osmosis? | water flows toward the higher concentration of solutes because it has a lower amount of water |
the force with which pure water moves into that solution as a result of its solute concentration | osmotic pressure |
what is osmolarity? | total solute concentration in an aqueous solution |
what is the effect of various osmotic solutions (water) on cells? | tonicity |
a solution that does NOT cause osmotic flow of water in or out of a cell | isotonic; iso=same tonos(tonic)=tension |
what does a cell do in a HPYOtonic solution? | cell swells/ruptures (hypo-think HIPPO->get big) |
what does a cell do in a HYPERtonic solution? | cell shrinks |
hypotonic has _____ solutes | less |
hypertonic has ____ solutes | more |
hypotonic ______ water through osmosis | loses |
hypertonic _____ water through osmosis | gains |
what are the two forms of carrier-mediated transport? | facilitated and active |
what are the three characteristics of channel-mediated transport? | specify, saturation limit, regulation |
what are the two mechanisms of channel mediated transport? | cotransport and countertransport |
what are 2 substances moving in the same direction at the same time called? | cotransport |
what is it called when 1 substance moving in while another moving out? | contertransport |
what occurs when carrier proteins transport molecules too large to fit through channel proteins? | facilitated diffusion |
where does a molecule bind to a protein? | the receptor site |
what are the two types of facilitated diffusion? | passive and carrier mediated |
what occurs in active transport? | move substances AGAINST THE CONCENTRAION GRADIENT from areas of low to high concentration |
what is needed for active transport? | energy |
sodium potassium exchange pump uses which type of transport? | active |
what does a sodium potassium exchange pump do? | moves 3 Na (sodium) out of cell and 2 K (potassium) into the cell |
secondary active transport does what? | drives glucose transport; ATP pumps the sodium back out |
transport vesicles are useful in what two cellular function? | endocytosis and exocytosis |
what are ligands? | receptors (glycoproteins) that bind target molecules |
what carries ligands and receptors into the cell? | coated vesicles(endosomes) |
what does lysosomes do? | break down things |
what does cell drinking refer to? | pinocytosis |
what does cell eating refer to? | phagocytosis |