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Pharm Lesson 2
The following are activities related to the key terms for the chapter.
| Question | Answer |
|---|---|
| Adverse drug reactions (ADRs) | Unintended side effects from medications such as cough, headache, nausea and so on |
| Anaphylactic reaction | A life-threatening reaction to a drug, insect/jellyfish sting, snake bite or foreign substance requiring immediate medical attention |
| Chemoinformatics | Application of computer technology, statistics and math to study information about the structure, properties and activities of molecules |
| Cumulative effect | Increased effect of a drug that accumulates in the body |
| Dependence | Acquired need for a drug after repeated use; may be psychological with craving and emotional changes or physical with body changes and withdrawal symptoms |
| Dosage | Amount of drug given for a particular therapeutic or desired effect |
| Drug interactions | Response that may occur when more than one drug is taken-The combination may alter the expected response of each individual drug |
| Drug processes | Four biological changes that drugs undergo within the body |
| Hypersensitivity | Allergic or excessive response of the immune system to a drug or chemical |
| Idiosyncratic reaction | Unusual reaction to a drug, other than expected |
| Local effect | Affecting one specific area or part |
| Paradoxical reaction | Opposite effect from that expected |
| Pharmacogenomics | The study of the effects of genetic differences among people and the impact that these differences have on the uptake, effectiveness, toxicity, and metabolism of drugs |
| Placebo effect | Relief from pain as the result of suggestion without active medication |
| Prodrug | A newly developed group of chemicals that exhibit their pharmacological activity after biotransformation |
| Sources of drugs | Five ways that the drugs are obtained being plants, minerals, animals, synthetic and DNA |
| Systemic effect | Affecting the whole body or system |
| Teratogenic effect | Effect of a drug administered to the mother that results in abnormalities in the fetus |
| Therapeutic range | A range of drug levels in the blood that will produce the desired effects without causing serious side effects |
| Tolerance | Decreased response to a drug after repeated dosage; greater amounts of the drug are required for the same effect |