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Histology: Muscle
WVSOM: Muscle TIssue
| Question | Answer |
|---|---|
| 3 connective tissue sheaths associated with muscle (from out to in) | Epimysium, parimysium, endomysium |
| Dark bands are made up of? | Thick fliaments, A-band, myosin filaments |
| Light bands are made up of? | Thin filament, I-bands, F-actin chains |
| How fibers move during contraction | Sliding motion over one another |
| Composition of M-line | binding protiens, creatine kinase and myomesin |
| Which bands reduce in contraction | H-bands and I-bands |
| What are the two types of muscle fibers | Type I (Red) and Type II (white) |
| Characterisitcs of type I (red) muscle | high myoglobin, highly vascular, lots of mitochondria, slow endurance, resistant to fatigue |
| Location of Type I muscle | postural muscles of cervical and lumbar regions and higher levels of upper and lower limbs |
| Characteristics of Type II (white) muscle | Low myoglobin, few mitochondria, low vascularity, easyily fatigued, fast movement, precise actions |
| Location of type II | eye muscles, but mixes with type I |
| 3 components of a motor unit | motor nueron, muscle fibers innervated by a single motor nueron and nueromuscluar junctions |
| What is a muscle spindle | a sensory receptor |
| what does a muscle spindle sense/detect | muscle tension and stretch |
| what are muscle spindles composed of | intrafusal fibers |
| what type of tissue surround muslce spindles | dense irregular |
| 3 types of muscle | cardiac, skeletal, and smooth |
| Describe Cardiac muscle | striated, single nucleus in the center of the cell, and branched. Involuntary and have intercalated disks |
| Describe skeletal muscle | striated, longer than caridac, multiple nuclei on edge of cell |
| Describe Smooth muscle | not striated, cigar shaped nuclei, single central nucleus |
| What is an intercalated disk | found in cardiac cells, bind cells together so that they work as a unit |
| what tyoe of cell adhesions are found in an intercalated disk | zonula adherens and desmosomes link the cell together, while gap junctions exist on lateral aspects |
| What are purkinge fibers | cells that are 4-5 times the size of a normal cell, found in the interventricula space, and relay information very fast |
| What are Nodal fibers | found in SA and AV nodes, set basic rhythum for the heart, smaller than normal cells |
| What are dense bodies | found in smooth muscle, serve much like Z-disks to help anchor filaments using a-actinin |
| Which muscle tissue is mitotically active? Give an example | smooth, menstral cycle |
| Can the regeneration of smooth muscle become pathological | YES |
| what cells are important for the formation of skeletal muscle | satellite cells |
| What is Rhabdomyoma | benign tumor of skeletal muscle |
| What is Leiomyosarcoma | malignant tumor of smooth muscle |
Created by:
lowryc
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