Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Microbio: RNA Virus
USMLE Step 1
| Bug | Pathology |
|---|---|
| Rhinovirus | naked Picornaviridae, common cold, transmitted by respiratory droplets & dried droplets |
| Echovirus | naked Picornaviridae aka enterovirus,fecal-PO transmission,enteric cytopathic human orphan virus,cause aseptic meningitis, upper respiratory infection and diarrhea |
| Hepatitis A | naked Picornaviridae aka enterovirus,fecal-PO transmission,cause infectious hepatitis A/acute viral hepatitis |
| Polio | naked Picornaviridae aka enterovirus,fecal-PO transmission,replicates in oropharynx & small intesting then go to bldstream & replicate in anterior horn killing cells,4 types:asx,abortive,non-paralytic & paralytic,type determined by pt's immune status |
| Coxsackie A | naked Picornaviridae aka enterovirus,fecal-PO transmission,HERPANGINA:fever,sore throat,tender vesicles in oropharynx(post 1/2),HAND-FOOT-MOUTH DISEASE:vesicular rash on hands & feet,& ulcers in mouth |
| Coxsackie B | naked Picornaviridae aka enterovirus,fecal-PO transmission,cause MYOCARITIS:leads to dilated cardiomyopathy & BORNHOLM DISEASE:pleurodynia='Devil's Grip',fever,pleuritic chest pain |
| Rotavirus | naked Reoviridae,fecal-PO transmission,cause pediatric gastroenteritis (#1 cause in children),replicates in small intestine mucosal cells,leads to diarrhea |
| Colorado Tick Fever | naked Reoviridae,vector:Dermacentor wood tick,reservoir:small rodents (chipmunk & squirrels),host:humans,occur in Rocky Mts,sxs:high fever,hemagglutination,retro-orbital pain,severe myalgia,remission several days then fever for several wks |
| Influenza A, B (enveloped Orthomyxoviridae) | respiratory transmission,sxs:fever,chills,hemagglutinin,myalgia,cough 3 dys in healthy,non-immunized individual,cause death in anyone w/ cardiac or pulmonary disease who isnt immunized,atypical pneumonia,2ndary bacterial pneumonia,Reye's syn w/ ASA |
| Influenza C | enveloped Orthomyxoviridae,sxs:fever,chills,hemagglutinin,myalgia,cough 3 dys in healthy,nonimmunized individuals,minor respiratory illness,no tx b/c self-limited,no vaccine |
| Rubeola: Measles, note 3 C's cough, coryza & conjunctivitis | envelope Paramyxoviridae,transmit by respiratory rt,enters upper respiratory 2 bld 2 RES 2 skin progressing as rash from face downwards,mortality >10% those die from encephalitis vs 40% are left deaf &/or mentally retarded,Koplik's Spots,prevent MMR,SSPE |
| Parainfluenza: Croup | enveloped Paramyxoviridae,has 4 serotypes,cause CROUP-subglottitis laryngotracheobronchitis,harsh barking cough & stridor (high pitched sound from turbulent flow in airway);'steeple sign' seen A-P neck XR due to swelling of soft tissue around trachea |
| Influenza A, B (enveloped Orthomyxoviridae) continued | A is endemic w/ potential to become pandemic due to surface glycoproteins H (hemagglutinin) & N (neuraminidase),B is epidemic,dx by FLU OIA or QUICKVUE or ZSTATFLU,tx w/ oseltamivir or zanamivir,prevention by vaccine of inactivated virus,1918 flu = shift |
| Mumps | enveloped Paramyxoviridae,results in parotitis (most common manifestation),orchitis & aseptic meningitis,can cause sterility esp post-puberty |
| Respiratory Syncytial Virus | enveloped Paramyxoviridae,bronchiolitis-pneumonia,#1 lower respiratory infection of infants,also major cause of otitis media in children & pneumonia in elderly,tx supportive + ribavirin,adults affect URT vs child affect LRT,2 serotypes |
| Rubella: German Measles | enveloped Togaviridae transmit via respiratory tract,sxs:fever,malaise,maculopapular rash on face spreads down (post auricular lymphadenopathy),mild & shorter than measles except 4 congenital acquired affect fetal heart,eye & brain,prevent w/ MMR vaccine |
| Coronavirus: Common Cold | enveloped Coronoviridae transmit via respiratory route,2nd most common cause of common cold |
| Coronavirus: Severe Acute Respiratory Syndrome (SARS) | enveloped Coronoviridae transmit via respiratory route,severe atypical pneumonia w/ high fever,nonprod cough,dyspnea,headache & hypoxia,CXR shows 'ground glass' infiltates w/o cavitation,dx PCR,tx:ribavirin+steroids |
| Alpha virus: Eastern Equine Encephalitis (EEE) | enveloped Togaviridae,various encephalitides are caused & all are arboviruses(ar = arthopod, bo = borne THUS arbo),vector:mosquito,reservoir:bird,host:human & horses cause encephalitis,high fever,50% fatal,southeast US |
| Alpha Virus: Western Equine Encephalitis (WEE) | enveloped Togaviridae,various encephalitides are caused & all are arboviruses(ar = arthopod, bo = borne THUS arbo),vector:mosquito,reservoir:bird,host:human & horses cause encephalitis,high fever,maybe fatal,mostly western US |
| St. Louis Encephalitis | enveloped Flaviviridae,vector:mosquito,reservoir:birds,hosts are humans ONLY,cause encephalitis-severe to fatal in the elderly,North America |
| Yellow (Flavi) Fever | enveloped Flaviviridae,vector:Aedes mosquito,reservoir:monkeys,hosts are humans ONLY,cause high fever,black vomitus,headache,sx free for several days, then fever+jaundice+hemorrhage,can b fatal,South America & Africa,Councilman bodies maybe seen in liver |
| Dengue Fever (Breakbone Fever) | enveloped Flaviviridae,vector:mosquito,reservoir:monkeys & humans,world-wide in warm,humid environments.sxs:high fever,rash,bone/joint pain,sx free then high fever w/ new rash |
| Dengue Hemorrhagic Fever | Dengue fever virus w/ re-exposure after having past hx of it causing high fever, shock due to hemorrhage, SEVERE-often fatal |
| West Nile Encephalitis | enveloped Flaviviridae,vector:mosquito,reservoir:birds,esp crows,hosts:humans,originally from Africa,now in Europe,Asia & US,sxs:fever,confusion,ascending muscle weakness & paralysis esp in > 60 yoa |
| California Encephalitis | enveloped Bunyaviridae,vector:mosquito,reservoir:rodents,host:humans,occurs mostly in North ctral US,sxs:mild w/ headache or severe w/ headache,confusion,fever,rarely causes death |
| Hantavirus Pulmonary Syndome | enveloped Bunyaviridae,RoBovirus (ROdent BOrne Virus),Hantavirus Sin Nombre,vector & reservoir:deer mice (urine,feces & saliva),host:human,transmission:respiratory rt,mostly in Western US,sxs:flu-like then acute respiratory failure,60% M&M w/ aid |
| Lyssavirus, note no tx, but vaccine | envelop Rhabdoviridae (Rabies),bullet-shaped capsid,infect any mammal by bite in2 skin,travels retrograde on sensory neurons 2 CNS,cause encephalitis & kills neurons,goes in2 salivary glands,+ Negri bodies,long incubation,sxs:hydrophobia,seizures,100% M&M |
| Ebola Hemorrhagic Fever | enveloped Filoviridae,sxs:fever,hemagglutination,v/d,thrombocytopenia,hemorrhage & shock,DIC,nearly 100% M&M,transmit via body fluids,hosts:monkeys & humans,reservoirs:unknown,bio-warfare agent,tx supportive |
| Norwalk Gastroenteritis | naked Calciviridae,fecal-PO rt,usually occurs @ schools,camps,on cruise ships,sxs:n/v/d x12-24 hrs |
Created by:
jerrica_08
Popular Medical sets